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Found 389 oncology trials

A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Interventional
This study investigates the use of medical cannabis as part of outpatient palliative care for patients with cancer. The purpose of this study is to assess how different approaches to symptom management can affect the quality of life in cancer patients who are new to palliative care.Participants will be randomly …
18 years or above
All genders
Observational
The purpose of this study is to investigate the long-term safety of a type of treatment called CAR T cell therapy. This study focuses on monitoring the long-term risks associated with this therapy, such as delayed adverse events and the persistence of modified T cells in the body.Participants in this …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and tolerability of genetically modified autologous T cells in patients with recurrent or refractory solid tumors. The T cells are engineered to express a receptor that recognizes a specific cancer-related protein called PRAME, which is often found in melanoma and other solid tumors. The study …
UPCC 28922 AbatacepT foR ImmUne checkpoint inhibitor associated Myocarditis (ATRIUM): A Phase 3, Investigator-Initiated, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Abatacept Compared to Placebo in Participants with Immune Checkpoint Inhibitor Associated Myocarditis
18 years or above
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication compared to a placebo in participants with myocarditis linked to immune checkpoint inhibitors (ICI). This condition can occur as a side effect of cancer treatments that use ICIs to enhance the body's immune response against cancer cells. The purpose of this …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the condition of locally advanced or metastatic solid tumors. It evaluates an investigational medication to understand its effects on this particular health issue.The purpose of this study is to evaluate the safety and effectiveness of the investigational medication. It assesses how well the medication is tolerated and …
18 years or above
All genders
Observational
This study investigates the creation of a registry and biosample repository for patients diagnosed with cancer or benign tumors who are undergoing radiotherapy. A biosample repository includes biological samples such as blood, urine, and tumor specimens, which are collected and stored for research purposes.Participants in this study will have their …
18 years - 85 years
All genders
Phase 4
Interventional
This study investigates methods for screening liver cancer in patients with cirrhosis or chronic hepatitis B. The purpose of this study is to compare two screening methods: one using ultrasound and a protein marker called AFP, and another using a biomarker called GALAD. Participants will be divided into two study …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness of an investigational medication compared to observation in treating intermediate risk non-muscle invasive bladder cancer (IR-NMIBC). The purpose of this study is to see if the investigational medication can help prevent the cancer from returning after the initial surgical removal of the tumor.Participants in the …
18 years - 130 years
All genders
Observational
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
18 years or above
Female
Phase 2
Interventional
This study investigates the effectiveness of a combination of investigational medications in treating ovarian cancer associated with ARID1A mutation. The purpose of this study is to evaluate how well the combination of these medications works against tumors in patients with recurrent or persistent clear cell or endometrioid ovarian cancer, which …
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