Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effectiveness and safety of an investigational medication, a bi-specific antibody-drug conjugate, for patients with advanced triple-negative breast cancer (TNBC) or ER-low, HER2-negative breast cancer (BC). These patients have not received prior treatment for their condition and are not eligible for certain standard therapies. The investigational medication …
This study investigates the safety and effectiveness of an investigational medication in patients with locally advanced or metastatic solid tumors that have a specific mutation in the TP53 gene called Y220C. The study is divided into different phases to assess the medication alone and in combination with another treatment. The …
This study investigates the safety and initial effects of an investigational medication in people with advanced or metastatic solid tumors that have changes in the MAPK pathway. The purpose of this study is to understand how the investigational medication affects these tumors and to determine the appropriate dosage for future …
This study investigates the safety and effectiveness of an investigational imaging agent used during lung cancer surgery. The purpose is to see if this agent can help identify cancerous tissue using near-infrared (NIR) imaging. Participants in this study will undergo surgery for lung cancer, and the investigational agent will be …
This study investigates the safety of combining immunotherapy and radiation therapy for treating urothelial bladder cancer. The purpose of this study is to determine if it is safe to use both treatments at the same time, which is not the usual approach. Safety will be assessed based on any acute …
This study investigates the use of image-guided surgery with indocyanine green for imaging solid tumors. The purpose is to evaluate the safety and effectiveness of this method compared to the standard surgical care. Patients involved are those with solid tumors or diseased tissue, including benign nodules, which are considered resectable …
This study investigates an investigational medication designed to treat patients with advanced or metastatic solid tumors. The purpose of this study is to discover if the investigational medication can slow or stop cancer growth and to learn about its safety. The study will focus on various types of advanced cancers, …
This study investigates the safety and effects of an investigational medication in adults with carcinoid syndrome. The purpose of this study is to evaluate how the investigational medication works in the body and its safety for people with this syndrome.Participants will first be randomly assigned to receive either the investigational …
This study investigates the effects of an investigational medication, ORIC-114, on patients with advanced solid tumors that show changes in certain genes known as EGFR or HER2. The purpose of this study is to determine the best dose for Phase 2 trials and to evaluate the safety and effectiveness of …
This study investigates the safety and effects of an investigational medication in people with advanced solid tumors that have a specific gene change called KRAS G12D mutation. The purpose of this study is to learn how the investigational medication works when given alone or with other cancer treatments.Participants in the …
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