Found 43 Lymphoma trials
A listing of Lymphoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study aims to determine the long-term effects of CTL019 on patients who were enrolled in UPCC 13413: "Phase IIa Study of Redirected Autologous T-Cells Engineered to Contain Anti-CD 19 Attached to TCR and 4- BB Signaling Domains in Patients with Chemotherapy Relapsed of Refractory CD 19+ Lymphomas". It also …
This study investigates the use of an investigational treatment, rapcabtagene autoleucel, for different types of blood cancers including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), diffuse large B-cell lymphoma (DLBCL), acute lymphoblastic leukemia (ALL), and high-risk large B-cell lymphoma (HR LBCL).The study consists of two phases. In Phase I, …
This study investigates the use of CAR T cells, a type of cell therapy, in treating patients with CD19+ cancers. The purpose of this study is to understand how safe and feasible it is to use these modified cells in patients whose cancer has come back or has not responded …
This study investigates an investigational medication for patients with advanced non-small cell lung cancer (NSCLC) and other solid tumors that have a specific change in the anaplastic lymphoma kinase (ALK) gene. The purpose of this study is to find out how safe and tolerable the investigational medication is, and to …
This study investigates the occurrence of irregular heart rhythms in patients with chronic lymphocytic leukemia (CLL) who are treated with Bruton’s Tyrosine Kinase (BTK) inhibitors. The purpose of this study is to use wearable technology to monitor heart rhythms and blood pressure at home, aiming to understand how often patients …
This study investigates the investigational medication in patients with relapsed or refractory T-cell lymphoma. The purpose of this study is to understand how the medication works in the body and its effects on the disease.The study evaluates the safety and tolerability of the investigational medication. Researchers are also looking at …
To explore secondary malignancies in subjects enrolled to the L-RAD study (IRB #832203, Lymphoproliferative Disorders: Biological Specimen Repository and Clinical Database) who received CAR T-cells or other T-cell directed therapies for lymphoproliferative disorders and to investigate potential relationships between prior T-cell directed therapy for lymphoma and subsequent malignancies.
Managed Access Program (MAP) to provide access to CTL019, for acute lymphoblastic leukemia (ALL) or diffuse large b-cell lymphoma (DLBCL) patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for commercial release. The primary purpose of a MAP is to provide access to product. NA - …
This study investigates the safety and feasibility of using investigational cells called huCART19-IL18 in patients with relapsed or refractory CD19+ cancers. These are cancers where the CD19 protein is present on the surface of malignant cells, such as certain types of lymphoma and leukemia. The purpose is to determine if …
The purpose of this study is to investigate the long-term safety of an investigational medication after participants have completed earlier clinical studies. This study will include individuals from previous studies, called originator studies, and will allow them to continue receiving treatment or follow-up visits. The study will use a master …
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