Found 43 Lymphoma trials
A listing of Lymphoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates hematologic malignancies. The purpose of this study is to assess the safety and feasibility of using autologous anti-CD45 CAR T cells in combination with CD45 base edited hematopoietic stem and progenitor cells.The study evaluates the effectiveness and safety of these treatments in patients who have relapsed or …
This study investigates the safety, tolerability, and effects of an investigational medication in individuals with blood cancers that have not responded to previous treatments. The purpose of this study is to determine how well the investigational medication works when used alone or in combination with other anticancer agents. Participants will …
This study investigates the long-term safety of investigational cell therapies in patients who have previously participated in Caribou-sponsored clinical studies, special access programs, or investigator-initiated trials (IITs). The purpose of this study is to observe patients over a period of up to 15 years after they have received their initial …
This study investigates the safety and tolerability of β-hydroxybutyrate (BHB) supplementation in patients receiving standard-of-care anti-CD19 CAR T-cells for the treatment of lymphoma. The purpose of this study is to determine if BHB supplementation, administered orally, affects the gut microbiome and peripheral blood mononuclear cells (PBMCs) in these patients.Participants will …
This study investigates the safety and tolerability of an investigational medication in patients with advanced solid tumors and lymphomas. The study is divided into two phases: Phase 1 focuses on finding the maximum tolerated dose of the investigational medication, while Phase 2 evaluates its antitumor activity across different types of …
This study investigates the use of an investigational medication, epcoritamab, before and after CAR-T cell therapy in patients with relapsed or refractory large B-cell lymphomas. This study aims to understand if epcoritamab can improve outcomes when used in conjunction with CAR-T cell therapy, a treatment where a patient's T cells …
This study investigates the use of unlicensed cryopreserved cord blood units (CBUs) for transplantation in pediatric and adult patients with hematologic malignancies and other conditions. The purpose of this study is to understand how well patients recover neutrophil levels, a type of white blood cell important for fighting infections, after …
This study investigates primary central nervous system lymphoma. The purpose of this study is to evaluate the safety and efficacy of an investigational medication as a first-line treatment for individuals who cannot undergo a transplant.The study evaluates the effectiveness and safety of the investigational medication in patients. It focuses on …
This study investigates providing access to an investigational medication for patients with serious or life-threatening conditions where standard treatments are not suitable. The study focuses on patients with out-of-specification leukapheresis products or out-of-specification manufactured cells for treatment. Leukapheresis is a procedure that involves removing white blood cells from the body, …
This study investigates the use of investigational medications following CAR T-cell therapy for individuals with relapsed or refractory large B-cell lymphoma and grade IIIB follicular lymphoma. The purpose of this study is to determine if additional treatment with investigational medications, after initial chemotherapy and CAR T-cell therapy, can better manage …
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