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Found 28 Liver Disease trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication in combination with immuno-oncology agents for individuals with advanced or metastatic solid tumors that cannot be surgically removed. The purpose of this study is to understand how the investigational medication, when used alone or with other treatments like nivolumab, …
UPCC 04219 Phase 2 Study of Capecitabine-Temozolomide(CapTem) with yttrium-90 Radioembolization in the Treatment of Patients with Unresectable Metastatic Grade 2/3 Neuroendocrine Tumors
18 years or above
All genders
Phase 2
Interventional
This study investigates the treatment of patients with unresectable metastatic neuroendocrine tumors (NETs) that are primarily located in the liver. The purpose of this study is to evaluate the effectiveness and safety of a combination treatment using Capecitabine-Temozolomide (CapTem) and yttrium-90 (Y90) radioembolization.Participants in the study will receive CapTem, which …
99 years or below
All genders
The overarching goal of our Clinical Validation Center for Hepatocellular Carcinoma (CVC-HCC) is to develop a robust infrastructure that will support efficient validation of emerging HCC biomarkers. Our CVC-HCC will also conduct studies to validate novel blood and imaging biomarkers to improve risk stratification and early detection in patients with …
99 years or below
All genders
PRIMARY OBJECTIVE: To conduct a multicenter, observational study of patients with well-characterized hepatic adenoma. At the end of the study, robust clinical information, central bio-repository of genomic DNA and liver tissue (where available) will be developed SECONDARY OBJECTIVE: To develop the well characterized hepatic adenoma biorepository with linked clinical data …
UPCC 34217 Analysis of Primary and Metastatic Colorectal Cancer
99 years or below
All genders
Colorectal cancer is amongst the top three leading causes of cancer and likewise, the third leading cause of cancer related mortality. In particular, there are limited therapeutic options for stage IV or metastatic CRC (to liver, lungs, and other sites), with 5-year survival being less than 10%. While preclinical model …
18 years - 80 years
All genders
The purpose of this study is to learn how to dialysis doctors can treat dialysis patients infected with Hepatitis C themselves. Hepatitis C infection is common in hemodialysis patients. There are new medications, such as Zepatier, which can cure hepatitis C in > 95% of patients. Zepatier is particularly good …
ANDROMEDA-SHOCK-2 Trial
18 years - 99 years
All genders
Septic shock is a disease of the circulatory system representing a complication of serious infections, and is associated with a very high mortality, since around 1/3 of patients with this condition die. This disease produces a series of alterations in the body, including failure of the heart, kidneys, liver, among …
18 years or above
All genders
Phase 2
Interventional
This study investigates the safety and effects of an investigational medication in adults with carcinoid syndrome. The purpose of this study is to evaluate how the investigational medication works in the body and its safety for people with this syndrome.Participants will first be randomly assigned to receive either the investigational …
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