Found 28 Liver Disease trials
A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of a medical device containing yttrium-90 for treating liver cancer, specifically Hepatocellular Carcinoma (HCC). The purpose of this study is to evaluate the safety and effectiveness of Eye90 microspheres, which deliver localized radiation therapy directly to liver tumors. This approach is used for patients whose …
To acquire baseline and serial HCC cancer core biopsy samples in order to characterize the epigenetic, proteomic, metabolomic and immunologic profile of hepatocellular carcinoma cells surviving TACE. See section 2 of full protocol. See section 3.2 full protocol. See section 3.3 full protocol.
This study investigates a treatment for liver metastases from neuroendocrine tumors. It aims to find the best dose and safety of a hypoxia-activating agent combined with embolization, a procedure that blocks blood flow to cancer cells. The agent, administered directly into the liver's arteries, is evaluated using MRI scans based …
This study investigates the effects of combining an investigational medication with another treatment for patients with metastatic colorectal cancer that primarily affects the liver. In this study, researchers are looking at how the combination treatment works and its safety for patients.Participants in the study will receive the investigational medication along …
The aims of this study are four-fold: (1) To determine if cholate clearance is related to underlying cardiovascular hemodynamics, specifically low CO, elevated CVP, desaturation as seen in the Fontan. (2) To characterize Fontan patients with elevated systemic HFR/portal HFR ratio. (3) To know whether cholate clearance is a reliable …
This study investigates the use of an investigational oncolytic immunotherapy called RP2 in combination with other treatments for patients with advanced liver and biliary tract cancers. Specifically, it looks at patients with hepatocellular carcinoma (HCC) that cannot be surgically removed or has returned or spread, and biliary tract cancer (BTC) …
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
The target population are patients at Penn Medicine undergoing elective bariatric surgery; and are additionally participating in POW-R study ( Protocol #843280) Patients will be recruited to undergo liver wedge and visceral adipose tissue biopsy and provide blood samples. Liver samples will be processed for RNA, metabolomics, and biochemical and …
This study investigates the effects of additional treatment after surgery for patients with high-risk well-differentiated pancreatic neuroendocrine tumors. The purpose of this study is to see if giving the investigational medications capecitabine and temozolomide after surgery can prevent or delay the return of cancer compared to just observing the patients …
To externally validate and refine prediction models for a) incident and b) subsequent KC in a prospective multi-center cohort of kidney and liver transplant recipients, with detailed data on UV exposure, skin type, and photosensitivity.
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