Found 75 Neoplasm Metastasis trials
A listing of Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
PPS Study- Screening and Classification of Pentosan-Associated Maculopathy in Patients with Interstitial Cystitis
The primary objective of this study is to determine the prevalence of retinal changes in patients using pentosan polysulfate sodium (PPS) for treatment of interstitial cystitis and further characterize this condition using multimodal imaging. Additionally, this study aims to identify additional clinical findings associated with PPS maculopathy and to gain …
The NICU Antibiotics and Outcomes Trial (NANO)
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes …
THE COMPARATIVE EFFECTIVENESS OF 7 VERSUS 21 HOME-DELIVERED MEDICALLY TAILORED MEALS TO IMPROVE MALNUTRITION RISK IN MALNOURISHED PATIENTS WITH HEART FAILURE: A RANDOM ORDER CROSSOVER FEEDING TRIAL (MEDIMEALS)
The objectives of the random order crossover design study are to compare the effectiveness of 7- versus 21- meals/week on the primary outcome of malnutrition risk score and secondary outcomes of unplanned emergency department visits or hospital readmissions and on diet quality. The primary outcome is the malnutrition risk score …
UPCC 07422 Intervening on Frailty to Improve Outcomes for Older Allogeneic Transplant Recipients
Please refer to Protocol Section 2.0, Study Objectives. Please refer to Protocol Sections 8.2, Primary Endpoints. Please refer to Protocol Sections 8.3, Secondary Endpoints.
Study Evaluating Safety and Efficacy of Venetoclax in combination with Azacitidine after allogeneic Stem Cell Transplantation in Subjects with Acute Myeloid Leukemia (AML) (VIALE-T)
Phase 3
Pleae refer to Section 3 (Objectives and Endpoints) of the full protocol Please refer to Section 3.1 (Primary Endpoint) of the full protocol Please refer to Section 3.2 (Secondary Endpoints) of the full protocol
UPCC 18121: A Phase II Study of NirAparib Dostarlimab and Radiotherapy in Metastatic PD-L1 Negative or Immunotherapy-Refractory Triple-Negative Breast Cancer (NADiR)
Phase 2
Please refer to Section 4 of the full protocol (Objectives) Please refer to Section 18.4 of the full protocol (Analysis of Primary Endpoints) Please refer to Section 18.5 of the full protocol (Analysis of Secondary and Exploratory Endpoints)
UPCC 29922: First-in-human open-label multicenter Phase I/IIa dose escalation trial with expansion cohorts to evaluate safety and preliminary efficacy of BNT142 in patients with CLDN6-positive advanced solid tumors
Phase 1
Please refer to Protocol BNT142-01, section 1.1 Trial synopsis, Objectives and endpoints. Please refer to Protocol BNT142-01, section 1.1 Trial synopsis, Objectives and endpoints. Please refer to Protocol BNT142-01, section 1.1 Trial synopsis, Secondary objectives.
UPCC 01622 Neoadjuvant PD-1 blockade in resectable Merkel cell carcinoma
Phase 1
Please refer to Protocol Section 3.0 (Objective(s), Hypothesis(es), and Endpoint(s). Please refer to Protocol Section 3.0 (Objective(s), Hypothesis(es), and Endpoint(s). Please reer to Protocol Section 3.2 (Secondary Objective(s), Hypothesis(es), and Endpoint(s)
Developing electrophysiological markers for clinical trials in autistic adults
The objective is to evaluate a candidate magnetoencephalography (MEG) biomarker, M50, for autism spectrum disorder (ASD) to evaluate group difference between cohorts of adults with ASD vs. typical development as well as stability over a 12-week period. A secondary objective is to determine if the EEG analog of the M50, …
