Found 19 Soft Tissue Sarcoma trials
A listing of Soft Tissue Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effects of an investigational medication targeting advanced or metastatic solid tumors, including sarcomas. The purpose of this research is to understand how the investigational medication, a recombinant humanized tetravalent antibody, interacts with the human death receptor 5 (DR5). The study aims to explore its potential therapeutic …
This study investigates the safety and effectiveness of an investigational antibody-drug conjugate in combination with an immune checkpoint inhibitor, with or without carboplatin, for individuals with extensive stage small cell lung cancer (ES-SCLC). The purpose of this study is to explore how these treatments work together in the first-line setting, …
This study investigates Li-Fraumeni Syndrome (LFS) and Li-Fraumeni-like (LFL) Syndrome, focusing on the increased cancer risk associated with changes in the TP53 gene. The purpose of this study is to collect and analyze clinical data and biological samples from patients with these conditions to better understand the relationship between genetic …
This study investigates the effectiveness and safety of an investigational medication combined with pembrolizumab as a first-line treatment for individuals with locally advanced or metastatic non-small cell lung cancer (NSCLC). The cancer must have a specific mutation called KRAS G12C and a PD-L1 tumor proportion score of 50% or higher. …
We propose an iterative approach to develop and pilot test a new mHealth behavioral intervention for AET adherence that is culturally tailored to Black breast cancer survivors. We will first use qualitative methods informed by Black breast cancer survivors to develop a blueprint of the intervention (Aim 1). We will …
This study investigates personalized medicine approaches to determine which investigational medications are most effective for different types of breast cancer tumors. The purpose is to identify early indicators of treatment response, such as tumor analysis before surgery using MRI images, tissue, and blood samples, to predict treatment success.Participants will undergo …
This study investigates the effect of adding radiation therapy to the usual treatment for patients with high-risk asymptomatic bone metastases. These metastases are defined by their location or size, such as those that are 2 cm or larger or located in critical areas like the hip, shoulder, or spine, and …
This study investigates the effectiveness of two surgical procedures in reducing the risk of ovarian cancer in individuals with BRCA1 mutations. The purpose of this study is to compare bilateral salpingectomy, which involves removing the fallopian tubes, with bilateral salpingo-oophorectomy, which involves removing both the fallopian tubes and ovaries. These …
This study investigates the effectiveness of active surveillance and chemotherapy in treating germ cell tumors. The purpose of this study is to see if monitoring patients who have low-risk tumors after surgery can help maintain high survival rates without immediate further treatment. The study also aims to determine whether carboplatin …
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