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Found 17 Inflammation trials

A listing of Inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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UPCC 65518 Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
18 years - 45 years
Accepts healthy volunteer
All genders
Phase 1
The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called [18F]NOS. A radioactive tracer is a type of imaging drug that is labeled with a radioactive tag and injected into the body.   - Between 18–45 years old    - Nicotine …
18 years or above
All genders
Phase 2
Interventional
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP).The study evaluates the effects of an investigational medication on the physical functioning of adults with CIDP.Who can participate: Adults aged 18 and older with a body weight of 150 kg or less and a confirmed diagnosis of typical CIDP may participate. Participants …
18 years or above
All genders
Phase 3
Interventional
This study investigates chronic inflammatory demyelinating polyneuropathy (CIDP).The study evaluates the effectiveness of an investigational medication compared to standard treatments in managing CIDP.Who can participate: Adults with CIDP on stable IVIg treatment and meeting specific health criteria can participate. Participants must have an INCAT score between 2 and 9 and …
99 years or below
All genders
The purpose of this study is to investigate the presence of tight junctions in gingiva of individuals with periodontitis and peri-implantitis compared to non-inflamed gingiva. We will examine the presence of tight junctions identified by E-cadherin and Zo1 in both periodontitis and peri-implantitis compared to that without inflammation. We will …
12 years - 99 years
All genders
Phase 2
The purpose of this study is to see if taking the study drug, Belumosudil, for 52 weeks in addition to your usual care and medication, will prevent Chronic Lung Allograft Dysfunction (CLAD) in participants who have a lung biopsy that shows evidence of rejection or inflammation to the transplanted lung(s). …
8 years or above
All genders
Phase 3
Interventional
The purpose of this study is to investigate acanthamoeba keratitis. It evaluates whether including topical corticosteroids can improve vision in patients with this condition.This study focuses on evaluating the effectiveness of topical corticosteroids in treating acanthamoeba keratitis. It looks at how these medications might affect vision improvement.Who can participate: Participants …
18 years or above
All genders
Phase 2
Interventional
The goal of this randomized clinical trial is to test the topical drug clascoterone in patients with pilonidal disease, which is a common, benign skin condition of the gluteal cleft. The main questions it aims to answer are:Does clascoterone improve the severity of pilonidal disease as scored by a physician?Does …
40 years - 80 years
All genders
The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes, which may be useful in the diagnosis, prognosis, and treatment of giant cell arteritis (GCA; temporal arteritis). Study participants are eligible if …
99 years or below
All genders
The goals of this study are to compare markers of inflammation between women and men with sickle cell disease (SCD) and to see how these markers are associated with pain from SCD. The duration of this study is 1 month, during which you would complete a blood draw every 5 …
Phase 2 Randomized Controlled Trial of Sildenafil Citrate for Treatment of Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury
18 years - 70 years
All genders
Phase 2
We are researching whether sildenafil (or a placebo) can improve cerebrovascular reactivity (CVR) in the brain for individuals with ongoing symptoms from a brain injury. CVR is the brain's ability to adjust blood vessel size to maintain proper blood flow based on its oxygen needs. Sildenafil, commonly known as Viagra, …
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