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Found 492 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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UPCC 09821 Phase 1/2 Study of Regn4336 (A Psmaxcd3 Bispecific Antibody) Administered Alone or in Combination with Cemiplimab in Patients with Metastatic Castration-Resistant Prostate Cancer
18 years or above
Male
Phase 1/2
Interventional
This study investigates the use of an investigational medication for individuals with metastatic castration-resistant prostate cancer. The purpose of this study is to understand the safety and effectiveness of the investigational medication when given alone or in combination with another investigational drug. The study is divided into two parts: Part …
99 years or below
All genders
The goal of the eREACH3 Study is to evaluate the implementation of digital tools into remote genetic services, evaluating uptake and use of digital tools and outcomes in representative clinical populations. Our primary endpoints will include uptake of services and digital alternatives (future amendments). We will use proportions and 95% …
65 years or above
All genders
Phase 3
Interventional
This study investigates different dosing strategies for CDK4/6 inhibitors in older patients with metastatic breast cancer (MBC). The purpose of the study is to compare standard dosing with a titrated dosing approach to see which helps patients tolerate the medication better and continue treatment longer.Participants will be randomly assigned to …
Accepts healthy volunteer
All genders
Observational
This study investigates Li-Fraumeni Syndrome (LFS) and Li-Fraumeni-like (LFL) Syndrome, focusing on the increased cancer risk associated with changes in the TP53 gene. The purpose of this study is to collect and analyze clinical data and biological samples from patients with these conditions to better understand the relationship between genetic …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
Hair Probe to Enhance Cerebral Optical Monitoring of Stroke
99 years or below
All genders
A novel device, developed at the University of Pennsylvania, utilizes diffuse correlation spectroscopy (DCS), which allows for real-time, continuous bedside monitoring of CBF using near infrared light. This non-invasive device holds great promise for monitoring cerebral hemodynamics in stroke patients. Prior work from our group has used this device to …
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of investigational medications following CAR T-cell therapy for individuals with relapsed or refractory large B-cell lymphoma and grade IIIB follicular lymphoma. The purpose of this study is to determine if additional treatment with investigational medications, after initial chemotherapy and CAR T-cell therapy, can better manage …
Army-SPRING
99 years or below
All genders
This study’s goal is to identify and validate a package of implementation strategies to promote reach, effectiveness, adoption, implementation and maintenance of ASIST among Suicide Intervention Officers (SIO) in the Connecticut Army National Guard. Aim 1: Finalize our formative research to develop the implementation package for SIOs and chaplains. Hypothesis …
UPCC 21317 Detection of Cell-Free Circulating Tumor DNA in Patients with Histopathologically/Molecularly Proven or Radiographically Suspected Glial Tumors
99 years or below
All genders
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …
99 years or below
All genders
The primary objective of this study is to determine the level of regret patients experience following the decision to pursue amputation and how the extent of patient-reported regret varies with respect to indication (neoplasm versus trauma versus infection). Our secondary objective is to examine how patient- and surgeon-specific factors (including …
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