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Found 376 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years and younger
All genders
Objective 1: Estimate efficacy of medical management with oral letrozole 10 mg daily for three consecutive days followed by vaginal misoprostol 800 mcg for treatment of EPL Objective 2: Assess side effects, adverse events, and patient acceptability associated with letrozole and misoprostol for medical management of EPL Our primary outcome …
 CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
18-99 years
All genders
Phase 3
Interventional
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
99 years and younger
All genders
Please refer to section 3 of the study protocol. Penn will only enroll participants into Part 3 of the study. PRIMARY OBJECTIVES The primary objective of Part 1 is to assess the safety, tolerability, and manufacturing feasibility of Descartes-08 in patients with GMG. Part 1 of the study follows an …
 A study assessing the efficacy and feasibility of virtual cardiac rehabilitation with remotely monitored exercise (VCR)
18-99 years
All genders
This will be an observational study to investigate the feasibility and efficacy of a home-based, tech enabled, remotely supervised, cardiac rehabilitation (CR) program in qualifying American adults who cannot participate in traditional center based rehab.This study aims to investigate the feasibility and effectiveness of Carda Healths remotely administered cardiac rehab …
 PBFT02-001- Phase 1B Study to Assess a Single Dose of PBFT02 Delivered into Adult Subjects with Fronto-Temporal Dementia (FTD) and Mutations in the Progranulin Gene (GRN)
35-75 years
All genders
Phase 1
This research is being done to study a new way to treat FTD in patients who have the GRN mutation. This process is called “gene therapy”. Gene therapy is an experimental technique that aims to replace the gene that is not working properly with a version of the gene that …
18-50 years
All genders
Interventional
COSMID is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. The goal of the COSMID trial is to answer the question: For patients with QoL-limiting diverticular disease, is elective colectomy more effective than best medical …
99 years and younger
All genders
The objective of this study is to determine whether visual pathway structure and function correlates with hallucination severity and treatment outcomes in Parkinson disease. The primary outcome variable is hallucination severity, which will be quantified using the PD-adapted Scale for the Assessment of Positive Symptoms (SAPS-PD), a standardized semi-structured instrument …
99 years and younger
All genders
This study will examine the safety and effectiveness of lofexidine/pregabalin compared to lofexidine/placebo for managing opioid withdrawal in an outpatient settings. The study timeline is Screening from 1-30 days; dosing for 1-7 days, and a sttudy medication taper on days 8, 9, 10; Day 8 is also 1st dose of …
 Effects of the Contraceptive Implant in Women with Sickle Cell Disease (SCD CURE)
18-45 years
Female
This research is being done to see if women who have sickle cell disease (SCD) experience any difference in their pain while using a hormonal implant as compared to when not using a hormonal implant (Nexplanon). We are seeking women between the ages of 18 and 45 who have been …
 REVOLUTION: Trial to Evaluate Immunotherapy Combinations with Chemotherapy for the Treatment of Patients with Previously Untreated Metastatic Pancreatic Adenocarcinoma
18-99 years
All genders
Phase 1
This is a phase 1 study that enrolls subjects with metastatic pancreatic adenocarcinoma. The purpose of this study is to learn about the safety and efficacy of a combination of 4 study drugs: ipilimumab (ipi), nab-paclitaxel (nP), gemcitabine (gem), and hydroxychloroquine (HCQ). This is an open-label, non-randomized, exploratory platform trial …
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