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Found 38 Small Cell Lung Cancer trials
A listing of Small Cell Lung Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Identification of actionable genetic alterations is critical to determining the appropriate therapy in unresectable non-small cell lung cancer (NSCLC). Red blood cells (RBCs) may be an abundant and long-lasting reservoir of detectable tumor DNA. A "liquid biopsy," using blood samples from patients with advanced NSCLC to identify targetable mutations from …
This study investigates the safety and clinical activity of an investigational medication in participants with advanced solid tumors that have a specific genetic mutation known as KRAS G12C. The purpose of this study is to evaluate how the investigational medication works in different phases, including dose escalation and expansion, to …
This study investigates the effectiveness of two different radiation therapy approaches, fractionated stereotactic radiosurgery (FSRS) and single fraction stereotactic radiosurgery (SRS), in treating patients with cancer that has spread to the brain. SRS involves delivering a single large dose of radiation to the tumor, while FSRS spreads the dose over …
This study investigates the safety and effectiveness of an investigational medication in combination with immuno-oncology agents for individuals with advanced or metastatic solid tumors that cannot be surgically removed. The purpose of this study is to understand how the investigational medication, when used alone or with other treatments like nivolumab, …
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
This study investigates the safety and effectiveness of an investigational oral medication designed to degrade SMARCA2 in patients with advanced or metastatic solid tumors that have a SMARCA4 mutation. The purpose of this study is to understand how the investigational medication affects the body, how it is processed by the …
This study investigates an investigational medication for adults with advanced MTAP-null solid tumors. The study aims to evaluate the safety and tolerability of the investigational medication alone and in combination with another treatment called docetaxel.Participants will receive the investigational medication orally, and their health will be monitored to assess the …
This study investigates how genetic testing can guide cancer treatment choices for patients with advanced solid tumors. The purpose is to use the genetic information from patients' tumor cells to match them with investigational combination therapies that target specific genetic mutations. This approach aims to control tumor growth and improve …
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