Found 36 Non-Small Cell Lung Cancer trials
A listing of Non-Small Cell Lung Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates non-squamous non-small cell lung cancer. It focuses on patients with advanced or metastatic forms of this condition who have previously been treated and do not have actionable genomic alterations.The study evaluates the effectiveness and tolerability of an investigational medication compared to standard care. It also involves an …
This study compares the impact of using a combination of drugs, ramucirumab and pembrolizumab, versus standard chemotherapy for treating advanced non-small cell lung cancer that is stage IV or recurrent. Ramucirumab blocks new blood vessel growth that tumors need, while pembrolizumab boosts the immune system to fight cancer. The trial …
The purpose of this study is to investigate the effect of adding an investigational medication to the immunotherapy drug durvalumab in patients with non-small cell lung cancer (NSCLC) who have undergone chemotherapy and surgery. The study aims to see if the combination of treatments can increase the time patients remain …
The purpose of this study is to investigate the effects of immune checkpoint inhibitors (ICI) on the heart and circulatory system in patients with breast cancer or non-small cell lung cancer. This study focuses on understanding how these medications, which are used in cancer treatment, might impact heart health. An …
This study investigates the safety, tolerability, and preliminary effectiveness of an investigational medication, either alone or in combination with another treatment, for patients with advanced solid tumors. The study includes patients with specific types of cancer, such as urothelial cancer and non-small cell lung cancer, who have not responded to …
This study investigates the effects of an investigational medication on patients with advanced solid tumors that have a KRAS G12D mutation. The purpose is to understand the safety and effectiveness of the investigational medication when used alone and in combination with other treatments.Participants in the study will receive the investigational …
This study investigates the safety and clinical activity of an investigational medication in participants with advanced solid tumors that have a specific genetic mutation known as KRAS G12C. The purpose of this study is to evaluate how the investigational medication works in different phases, including dose escalation and expansion, to …
This study investigates the safety and effectiveness of an investigational medication in combination with immuno-oncology agents for individuals with advanced or metastatic solid tumors that cannot be surgically removed. The purpose of this study is to understand how the investigational medication, when used alone or with other treatments like nivolumab, …
This study investigates an investigational medication for patients with advanced non-small cell lung cancer (NSCLC) and other solid tumors that have a specific change in the anaplastic lymphoma kinase (ALK) gene. The purpose of this study is to find out how safe and tolerable the investigational medication is, and to …
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
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