Found 24 Colorectal Cancer trials
A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the impact of a decision aid on colorectal cancer screening behaviors among older adults with low health literacy. The purpose of this study is to see if a newly developed decision aid pamphlet can influence the screening intentions of adults aged 75-85, who may have different risk …
This study investigates treatment options for patients with advanced or metastatic colorectal cancer that is resistant to standard therapies. The purpose is to compare two treatments: one with a combination of two investigational medications and another with one investigational medication alone. The cancer can spread to other parts of the …
This study investigates the use of circulating free-DNA (cfDNA) markers in blood to improve detection of colorectal cancer (CRC) and advanced adenomas. The purpose of this study is to collect blood samples and clinical data from participants in order to optimize a biomarker panel for better detection of these conditions.Participants …
This study investigates the effects of an investigational medication on patients with advanced solid tumors that have a KRAS G12D mutation. The purpose is to understand the safety and effectiveness of the investigational medication when used alone and in combination with other treatments.Participants in the study will receive the investigational …
This study investigates an investigational therapy using autologous CAR T-cells targeting Cadherin 17 (CDH17) for patients with advanced gastrointestinal cancers. These cancers have either returned after treatment or did not respond to standard treatments. The study aims to evaluate the safety and effectiveness of this therapy in patients with specific …
This study investigates the safety and clinical activity of an investigational medication in participants with advanced solid tumors that have a specific genetic mutation known as KRAS G12C. The purpose of this study is to evaluate how the investigational medication works in different phases, including dose escalation and expansion, to …
This study investigates the effects of total ablative therapy compared to usual systemic therapy in patients with limited metastatic colorectal cancer. Colorectal cancer can spread to other parts of the body, and this study focuses on cases where it has spread to up to four sites. Ablative therapy aims to …
Colorectal cancer is amongst the top three leading causes of cancer and likewise, the third leading cause of cancer related mortality. In particular, there are limited therapeutic options for stage IV or metastatic CRC (to liver, lungs, and other sites), with 5-year survival being less than 10%. While preclinical model …
This study investigates the treatment of KRAS-mutated cancers. The purpose of this study is to evaluate the safety and preliminary effectiveness of a new investigational treatment in patients with specific types of cancer that have a KRAS mutation.The study focuses on assessing the safety and how well the investigational treatment …
This study investigates a DNA screening technique to detect colorectal cancer in patients with Lynch syndrome. The purpose of this study is to evaluate how well a specific DNA test, called the multitarget stool DNA (mt-sDNA) 2.0 test, works in identifying colorectal cancer in these patients.Participants in this study will …
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