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Found 52 Solid Tumors trials

A listing of Solid Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 1/2
Interventional
This study investigates the condition of locally advanced or metastatic solid tumors. It evaluates an investigational medication to understand its effects on this particular health issue.The purpose of this study is to evaluate the safety and effectiveness of the investigational medication. It assesses how well the medication is tolerated and …
18 years or above
All genders
The purpose of this study includes the following: ·         To test the efficacy and safety of the Study Drug and to find out what effects, good and/or bad, it has on you and your cancer. ·         To understand how the body absorbs and processes the Study Drug by measuring the …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety, tolerability, and effectiveness of an investigational medication combined with pembrolizumab in individuals with advanced solid tumors. The purpose of this study is to identify the best doses for future research and to understand how the body processes and responds to the treatment.Participants will receive the …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
UPCC 22921 An Open-Label, Multicenter, First-in-Human, Dose-Escalation Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
12 years - 85 years
All genders
Phase 1
Interventional
This study investigates the effects of an investigational medication targeting advanced or metastatic solid tumors, including sarcomas. The purpose of this research is to understand how the investigational medication, a recombinant humanized tetravalent antibody, interacts with the human death receptor 5 (DR5). The study aims to explore its potential therapeutic …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication, either alone or with standard cancer treatments, in patients with advanced solid tumors, including urothelial cancer, that have a change in the FGFR3 gene. The purpose of this study is to learn more about how the investigational medication works …
18 years or above
Female
Phase 1
Interventional
This study investigates the safety and tolerability of an investigational medication for women with hormone receptor-positive (HR+) and human epidermal growth factor receptor 2 negative (HER2-) metastatic breast cancer. The study focuses on participants whose tumors have mutations in the PIK3CA gene. The purpose is to find the safest and …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates an investigational medication designed to treat patients with advanced or metastatic solid tumors. The purpose of this study is to discover if the investigational medication can slow or stop cancer growth and to learn about its safety. The study will focus on various types of advanced cancers, …
18 years - 100 years
All genders
Phase 1/2
Interventional
This study investigates an investigational medication for adults with advanced MTAP-null solid tumors. The study aims to evaluate the safety and tolerability of the investigational medication alone and in combination with another treatment called docetaxel.Participants will receive the investigational medication orally, and their health will be monitored to assess the …
18 years - 130 years
All genders
Observational
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …