Found 52 Solid Tumors trials
A listing of Solid Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates solid tumors. Participants will provide clinical data and biological samples to support cancer biomarker research.The focus of this study is to evaluate the development of tests for cancer detection and assessing the risk of cancer recurrence.Who can participate: Adults aged 18 and older with a confirmed diagnosis …
To assess safety and tolerability, including dose-limiting toxicities (DLTs), maximum tolerated dose (MTD), or maximum administered dose (MAD; if no MTD is defined) of IMGN151 when administered intravenouslyTo determine recommended Phase 2 dose (RP2D) for IMGN151To characterize the pharmacokinetics (PK) and immunogenicity of IMGN151 -To assess ORR for IMGN151 using …
This study investigates the use of image-guided surgery with indocyanine green for imaging solid tumors. The purpose is to evaluate the safety and effectiveness of this method compared to the standard surgical care. Patients involved are those with solid tumors or diseased tissue, including benign nodules, which are considered resectable …
This study investigates the effects of an investigational medication, ORIC-114, on patients with advanced solid tumors that show changes in certain genes known as EGFR or HER2. The purpose of this study is to determine the best dose for Phase 2 trials and to evaluate the safety and effectiveness of …
This study investigates the safety and effects of an investigational medication in people with advanced solid tumors that have a specific gene change called KRAS G12D mutation. The purpose of this study is to learn how the investigational medication works when given alone or with other cancer treatments.Participants in the …
Study of Investigational Medication in Patients with Advanced Cancers that Form in Organs or Tissues
This study investigates an investigational medication in patients with advanced or metastatic solid tumors. The purpose of the study is to evaluate the safety, tolerability, and dose-limiting toxicities (DLTs) of the investigational medication. The study will also determine the maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE) in …
This study investigates the safety and pharmacokinetics of an investigational medication, ROSE12, in patients with locally advanced or metastatic solid tumors. The study is conducted in three parts: a dose-escalation part to determine the safe dose, a biopsy part to evaluate biomarkers, and an expansion part to further assess the …
This study investigates the safety and effects of an investigational medication in participants with advanced solid tumors. The purpose of this study is to find the right dose of the investigational medication and to see how well it works in treating these tumors. Participants will have recurrent or metastatic solid …
This study investigates the safety and initial effects of an investigational medication in people with advanced or metastatic solid tumors that have changes in the MAPK pathway. The purpose of this study is to understand how the investigational medication affects these tumors and to determine the appropriate dosage for future …
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
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