Found 390 Neoplasms trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of ultrahypofractionated whole pelvis proton therapy with a brachytherapy boost for patients with high risk or unfavorable intermediate risk prostate cancer. This study aims to understand the effectiveness of this treatment method for those with a higher risk of cancer spreading to lymph nodes.Participants in …
This study investigates PARP-1 expression in men with metastatic prostate cancer using a special imaging technique called PET/CT scans. The purpose of this study is to observe how a radiotracer, which is a substance used to highlight areas of the body in imaging tests, interacts with cancerous sites in the …
This study investigates the safety and effectiveness of an investigational CAR T-cell therapy in adults with metastatic prostate cancer. CAR T-cell therapy is a treatment where a patient's T-cells, a type of immune cell, are modified to better recognize and attack cancer cells. The purpose of this study is to …
This study investigates the use of an investigational medication in treating patients with Kaposi sarcoma. The purpose of this study is to evaluate how well the investigational medication works by blocking certain enzymes needed for tumor cell growth, which may stop the tumor from growing.Participants will receive the investigational medication …
This study investigates the safety and effectiveness of two investigational medications in treating HER2-negative metastatic breast cancer. The study involves two investigational medications given in sequence, either trastuzumab deruxtecan followed by datopotamab deruxtecan or vice versa, to understand if this approach works for patients who have already tried other similar …
This study investigates the safety and feasibility of using T-cell receptor engineered donor T-cells in patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or acute lymphoblastic leukemia (ALL) who receive transplants from specific types of donors. The …
This study investigates the safety and appropriate dosing of investigational cells in patients with T Cell Non-Hodgkin Lymphoma. The purpose of this study is to determine how well these cells can be tolerated by patients and to identify the best dose for future studies. The focus is on patients whose …
This study investigates the effectiveness of a self-management program for head and neck cancer survivors who experience lymphedema and fibrosis. The purpose of this study is to evaluate how well the self-management program can help manage these conditions and improve the quality of life for participants.Participants will be assigned to …
The purpose of this study is to investigate communication strategies to increase the uptake of the HPV vaccine among adults. The study focuses on finding effective ways to communicate the importance of the HPV vaccine to adults, as the vaccination rates are currently low in this group.Participants in this study …
This study investigates the effectiveness of a quantitative HER2 assay in distinguishing between patients with HER2 IHC1+ metastatic breast cancer who respond to treatment and those who do not. The purpose is to determine if this assay can reliably identify patients who are likely to benefit from receiving investigational medications …
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