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Found 20 Prostate Cancer trials

A listing of Prostate Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 1
Interventional
This study investigates an investigational medication for people with advanced or metastatic solid tumors. The purpose of the study is to evaluate the safety and tolerability of the investigational medication when given alone or in combination with another treatment. The study focuses on patients with tumors that have a specific …
45 years - 99 years
Male
The objectives of this proposal are to: 1) describe the incidence of depression and trajectory of depressive symptoms; 2) identify potential determinants of depression; and 3) characterize the consequences of depression in a large, international cohort of patients with PC and in subgroups of this population during early and late …
UPCC 09821 Phase 1/2 Study of Regn4336 (A Psmaxcd3 Bispecific Antibody) Administered Alone or in Combination with Cemiplimab in Patients with Metastatic Castration-Resistant Prostate Cancer
18 years or above
Male
Phase 1/2
Interventional
This study investigates the use of an investigational medication for individuals with metastatic castration-resistant prostate cancer. The purpose of this study is to understand the safety and effectiveness of the investigational medication when given alone or in combination with another investigational drug. The study is divided into two parts: Part …
UPCC 18809 A Phase II Trial of Proton Radiation Therapy or Intensity Modulated Radiation Therapy using Mild Hypofractionation for Low- and Intermediate-Risk Adenocarcinoma of the Prostate
18 years or above
Male
Observational
This study investigates the use of proton radiation therapy or intensity modulated radiation therapy (IMRT) with mild hypofractionation for treating low- and intermediate-risk adenocarcinoma of the prostate. The purpose of this study is to explore the feasibility of these radiation therapies in improving cancer control and reducing side effects.Participants in …
99 years or below
All genders
This study investigates metastatic castration-resistant prostate cancer. It looks at how talazoparib, alone or with enzalutamide, affects this condition.Researchers are evaluating the effect of talazoparib, both alone and in combination with enzalutamide, on the progression of the cancer. They are interested in understanding how these treatments work in people who …
18 years or above
Male
Phase 3
Interventional
This study investigates the effectiveness of an investigational medication in combination with best supportive care for patients with metastatic castration-resistant prostate cancer (mCRPC). The study aims to compare the overall survival of participants receiving the investigational medication with those receiving a placebo, both alongside best supportive care.Participants in the study …
12 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and effectiveness of an investigational medication in patients with locally advanced or metastatic solid tumors that have a specific mutation in the TP53 gene called Y220C. The study is divided into different phases to assess the medication alone and in combination with another treatment. The …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the condition of locally advanced or metastatic solid tumors. It evaluates an investigational medication to understand its effects on this particular health issue.The purpose of this study is to evaluate the safety and effectiveness of the investigational medication. It assesses how well the medication is tolerated and …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication in combination with immuno-oncology agents for individuals with advanced or metastatic solid tumors that cannot be surgically removed. The purpose of this study is to understand how the investigational medication, when used alone or with other treatments like nivolumab, …
18 years - 130 years
All genders
Observational
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
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