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Found 20 Prostate Cancer trials

A listing of Prostate Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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UPCC 08821 Evaluating in vivo PARP-1 expression with 18F-FluorThanatrace positron emission tomography (PET/CT) in Patients with Metastatic Prostate Cancer
18 years or above
Male
Observational
This study investigates PARP-1 expression in men with metastatic prostate cancer using a special imaging technique called PET/CT scans. The purpose of this study is to observe how a radiotracer, which is a substance used to highlight areas of the body in imaging tests, interacts with cancerous sites in the …
18 years - 130 years
Male
Phase 1/2
Interventional
This study investigates the safety and effectiveness of an investigational CAR T-cell therapy in adults with metastatic prostate cancer. CAR T-cell therapy is a treatment where a patient's T-cells, a type of immune cell, are modified to better recognize and attack cancer cells. The purpose of this study is to …
18 years or above
Male
Phase 3
Interventional
This study investigates the effectiveness of adding enhanced therapy to standard treatment for prostate cancer patients experiencing biochemical recurrence. The study aims to compare standard prostate radiation therapy combined with short-term androgen deprivation to an enhanced therapy regimen that includes additional medications. Another aspect of the study examines the use …
18 years or above
Male
Phase 3
Interventional
This study investigates metastatic castration-resistant prostate cancer (mCRPC). The purpose of this study is to compare the effectiveness of an investigational medication, ifinatamab deruxtecan, against standard chemotherapy in extending the lives of participants and delaying cancer progression.Participants in the study will receive either the investigational medication or chemotherapy. The study …
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of ultrahypofractionated whole pelvis proton therapy with a brachytherapy boost for patients with high risk or unfavorable intermediate risk prostate cancer. This study aims to understand the effectiveness of this treatment method for those with a higher risk of cancer spreading to lymph nodes.Participants in …
18 years or above
Male
Interventional
The purpose of this study is to investigate the impact of Gene Expression Classifier (GEC) testing on prostate cancer care. This study involves men with newly diagnosed favorable risk prostate cancer. Participants will be assigned to one of two study arms: the intervention arm or the control arm. The control …
18 years or above
Male
Observational
The purpose of this study is to investigate prostate cancer in individuals who have a genetic risk for the disease. Prostate cancer is a common cancer in men, especially those with inherited genetic changes in certain genes like BRCA1, BRCA2, ATM, TP53, and HOXB13. These genetic changes can increase the …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and tolerability of an investigational medication in patients with advanced solid tumors and lymphomas. The study is divided into two phases: Phase 1 focuses on finding the maximum tolerated dose of the investigational medication, while Phase 2 evaluates its antitumor activity across different types of …
99 years or below
All genders
In this secondary use protocol, we will analyze de-identified data from a funded VA study called the Veterans Affairs Multi-omic Platform for Prostate Cancer (VA-MAPP) shared with our team through a fully executed data use agreement with the Greater Los Angeles VA and Penn Medicine to study the genetics of …
40 years or above
Accepts healthy volunteer
Male
This study investigates ways to detect prostate cancer earlier in people at genetic risk for aggressive disease, which forms, grows, or spreads quickly. The purpose is to study samples of blood, urine, and tissue in the laboratory to better understand the genetics of prostate cancer. This research aims to identify …
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