Found 48 Lung Cancer trials
A listing of Lung Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effectiveness of an investigational medication combined with chemotherapy compared to another treatment with chemotherapy for patients with advanced non-small cell lung cancer. The focus is on those with a specific protein expression called PD-L1. The study aims to understand how well the investigational medication works in …
This study investigates the use of an investigational imaging agent for lung cancer surgery. The purpose of this study is to explore the effectiveness and safety of a single dose of a fluorescence imaging agent administered through intravenous infusion. This agent is used during surgical procedures for patients with Stage …
This study investigates the use of investigational medications for treating metastatic non-small cell lung cancer (mNSCLC) in patients whose tumors express PD-L1. The purpose of this study is to compare the effectiveness and safety of two treatments: one investigational medication and a standard treatment, pembrolizumab. Participants will be randomly assigned …
This study investigates the use of investigational medications for treating advanced or metastatic non-small cell lung cancer (NSCLC) with a specific genetic mutation known as KRAS G12C. The purpose of this study is to compare the effects of calderasib, a targeted therapy, combined with subcutaneous pembrolizumab, against a combination of …
This study investigates treatment options for patients with non-small cell lung cancer (NSCLC) that have mutations in the epidermal growth factor receptor (EGFR) gene. Patients in this study have experienced disease progression despite previous treatment with EGFR tyrosine kinase inhibitors, which are medications that block signals promoting cancer cell growth.Participants …
This study investigates treatments for non-small cell lung cancer (NSCLC). The purpose of this study is to evaluate the effectiveness of investigational agents, alone or in combination with pembrolizumab and chemotherapy, in treating NSCLC. Pembrolizumab is a type of immunotherapy that helps the immune system fight cancer cells. The study …
This study investigates treatment options for non-small cell lung cancer (NSCLC), focusing on patients who undergo surgery. The purpose is to determine if adding an investigational medication to pembrolizumab post-surgery is more effective in preventing disease recurrence in patients who did not achieve a pathological complete response (pCR) after initial …
This study investigates the effectiveness of a combination of three investigational medications in treating advanced non-small cell lung cancer (NSCLC). The purpose of this study is to see if these medications can shrink tumors or slow their growth in participants who have previously received chemotherapy and immunotherapy.Participants in this study …
A single-dose, open-label, dose-escalation Phase 1b study in patients scheduled to undergo minimally invasive surgery (MIS) for known or suspected lung cancer via thoracoscopy (i.e., VATS). Single dose IV administration of Pemofolacianine for Injection, either on the day before surgery or on the day of surgery, with 2 different doses …
This study compares the impact of using a combination of drugs, ramucirumab and pembrolizumab, versus standard chemotherapy for treating advanced non-small cell lung cancer that is stage IV or recurrent. Ramucirumab blocks new blood vessel growth that tumors need, while pembrolizumab boosts the immune system to fight cancer. The trial …
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