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Found 48 Lung Cancer trials

A listing of Lung Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and feasibility of using a type of adoptive cell therapy called CAR T cells in patients with FRa+ cancers. The purpose of this study is to assess how well these modified T cells can be administered directly into the pleural space, which is the area …
50 years - 80 years
All genders
Interventional
This study investigates the use of telehealth strategies to improve shared decision-making (SDM) visits for lung cancer screening (LCS). Lung cancer screening often involves low-dose computed tomography (LDCT), which can reduce lung cancer mortality but also carries risks. Patients are recommended to complete an SDM visit to discuss these risks …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates an investigational medication designed to treat patients with advanced or metastatic solid tumors. The purpose of this study is to discover if the investigational medication can slow or stop cancer growth and to learn about its safety. The study will focus on various types of advanced cancers, …
18 years or above
All genders
Phase 3
Interventional
The purpose of this study is to investigate the effect of adding an investigational medication to the immunotherapy drug durvalumab in patients with non-small cell lung cancer (NSCLC) who have undergone chemotherapy and surgery. The study aims to see if the combination of treatments can increase the time patients remain …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness and safety of using Tumor Treating Fields (TTFields) in combination with pembrolizumab and platinum-based chemotherapy for treating metastatic non-small cell lung cancer (NSCLC). The purpose of this study is to assess how well patients survive overall and how long they live without the disease getting …
12 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and effectiveness of an investigational medication in patients with locally advanced or metastatic solid tumors that have a specific mutation in the TP53 gene called Y220C. The study is divided into different phases to assess the medication alone and in combination with another treatment. The …
UPCC 03522 A Phase 1/2, Umbrella Study With Rolling Arms of Investigational Agents, With Pembrolizumab With or Without Chemotherapy in Treatment-Naive Participants With Stage IV Non-small Cell Lung Cancer (NSCLC)
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of investigational medications in combination with pembrolizumab, with or without chemotherapy, for people with Stage IV non-small cell lung cancer (NSCLC). The purpose of this study is to evaluate the safety and effectiveness of these treatment combinations in participants who have not previously received treatment …
18 years or above
All genders
Observational
This study investigates the safety and effectiveness of standard care treatments in patients with a type of lung cancer known as Epidermal Growth Factor Receptor (EGFR)-mutated Non-Small Cell Lung Cancer (NSCLC). The purpose of this study is to observe patients who are receiving standard care treatments, which may include a …
99 years or below
All genders
Phase 1
This is an investigator-initiated, open label phase Ib study examining 2nd line atezolizumab and tocilizumab in a cohort of recurrent/metastatic non-small cell lung cancer patients who have received prior immune checkpoint inhibitor therapy with or without other forms of therapy (i.e. chemotherapy, radiation). Patients with driver mutations in EGFR, ALK, …
Validation of the prospective registry of outcomes in patients electing lung transplantation (PROPEL)
18 years - 99 years
All genders
The research study is being conducted to develop a test to predict a common complication after lung transplant called primary graft dysfunction (PGD). Predicting PGD before using donor organs may help reduce deaths and improve outcomes of patients receiving a lung transplant in the future.
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