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Found 205 Type 2 Diabetes Mellitus trials

A listing of Type 2 Diabetes Mellitus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Depemokimab compared with mepolizumab for relapsing or refractory EGPA on standard of care therapy
18-90 years
All genders
Phase 3
The purpose of this study is to learn more about eosinophilic granulomatosis with polyangiitis (EGPA) that returns (relapse) or has not responded to treatment, and if the investigational drug depemokimab can improve the disease.  This study is being done to help determine if depemokimab is safe and how it works …
18-99 years
All genders
Phase 2
To evaluate the clinical response of multiple dose strengths of CIN-103 relative to placebo on abdominal pain and stool consistency (as a composite responder) in subjects with IBS-D (Irritable Bowel Syndrome Prominently Diarrhea) over 12 weeks of treatment and the safety and tolerability of multiple dose strengths of CIN-103 relative …
99 years and younger
All genders
Phase 3
Systemic sclerosis is a rare chronic autoimmune connective tissue disease. B cells have been reported to play a central role in the pathogenesis of SSc and B cell depletion has been shown to offer benefit to patients with SSc. Belimumab is a monoclonal antibody, which inhibits the survival of B …
 Study to Investigate the Efficacy and Safety of NS-229 in the Treatment of EGPA
18-90 years
All genders
Phase 2
The main purpose of this study is to learn how well the investigational drug NS-229 works and how safe NS-229 is compared with placebo.  An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA) to treat EGPA.   Participants could be in the …
99 years and younger
All genders
I am requesting a reliance agreement with the external IRB Advarra. The purpse is to treat a single patient with gastroparesis who has requested expanded access with tradipitant.By doing so, we will also monitor the efficacy of tradipitant in reducing individual symptoms associated with gastroparesis in this single patient and …
99 years and younger
All genders
Long-term Safety and Tolerability Study of Linerixibat for the Treatment of Cholestatic Pruritus in Participants with Primary Biliary Cholangitis
 NONCOMPACT- International Consortium for Multimodality Phenotyping in Adults with Non-compaction
18-99 years
All genders
This is a prospective, multicenter observational study to identify clinical, genetic and imaging predictors of clinical outcome in patients with suspected non-compaction cardiomyopathy  Many healthy people have increased trabeculations without consequences, however, some may develop blood clots, heart rhythm disorders or heart failure later in life. Currently we cannot predict who …
 INFINITY-Prospective Cohort Study of Mechanistic Associations between Intra-Myocardial Fat Deposition and Ventricular Tachycardia in Ischemic Cardiomyopathy
18-99 years
All genders
This study will focus on fat buildup inside the heart muscle, a newly recognized factor that makes patients vulnerable to such fast heart rates, or ventricular tachycardia, after a heart attack. This work may identify more successful strategies for curing dangerously fast heart rates. Adult subjects with prior history of …
 ConTTRibute: Global Observational Multicenter Long-Term Study of Patients with Transthyretin (TTR)-Mediated Amyloidosis
18-99 years
All genders
Phase 3
This is a prospective global multicenter long-term observational study designed to document the clinical outcomes of patients with hereditary transthyretin-mediated amyloidosis or wild-type transthyretin-mediated amyloidosis and the safety of patisiran (Onpattro) when used in patients with ATTRv amyloidosis. This is data collection study only and no study medication no visits …
 Studying symptomatic Transthyretin Amyloid Cardiomyopathy for those who Completed the Phase 3 ATTRibute-CM Trial (AG10-301)
18-99 years
All genders
Phase 3
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
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