Found 26 Type 2 Diabetes Mellitus trials
A listing of Type 2 Diabetes Mellitus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study is being done to find out if inhaled insulin given for a meal is safer and better to use than a bolus of insulin through the pump when exercising following a meal.
The purpose of this study is to find the effects of taking different doses of the thyroid medication levothyroxine in older people who already take levothyroxine for hypothyroidism. Older people are more likely to have problems when their dose of levothyroxine is too strong. Allowing lower doses of levothyroxine would …
This study investigates the use of continuous glucose monitoring (CGM) in pregnant women. It focuses on managing high blood sugar levels during early pregnancy.The study evaluates potential effects on the baby and the mother, including baby's size, shoulder injuries, and mother's blood pressure during pregnancy.Who can participate: Pregnant women aged …
Through participation in this study, UPenn will become a TrialNet Natural History Study affiliate site. TrialNet, (short title) began in 2004 and has screened over 240,000 family members for diabetes related antibodies. This specific Pathway to Prevention TrialNet study (TN-01) plans to perform baseline and repeat assessments over time in …
The purpose of the study is to determine the changes in muscle metabolites by MRI before and after exercise. The MRI will be performed while performing mild exercise of the calf muscle for 1-3 minutes. We are actively recruiting adults between 45-55 and 70-84. Volunteers cannot have diabetes, liver disease, kidney …
Emergence and Progression of Abnormal Glucose Tolerance in Cystic Fibrosis (Aim 1) (CF Longitudinal)
The purpose of this research study is to test how high blood sugar develops and worsens over time in some people with cystic fibrosis.If you agree to take part, your participation can last for up to 7 years.As a participant in this research, all participants will:Complete overnight fastingComplete Mixed Meal …
The primary objectives are to determine the pharmacokinetic (PK) and pharmacodynamic (PD) response of dorzagliatin 75 mg twice daily following 7-day administration in individuals with PI-CF and abnormal glucose tolerance (EGI, IGT or CFRD) when compared to 7-day administration of placebo according to a randomized, double-blind cross-over study design. The …
The purpose to evaluate whether outcomes in pregnant individuals with gestational diabetes randomized to metformin are not inferior to those in pregnant individuals randomized to insulin for the composite adverse neonatal outcome. Participants will be randomized to treatment with either insulin or metformin. Study visits include monthly check in visits, …
This study investigates the feasibility and tolerability of an investigational medication in patients with advanced lung disease. Advanced lung diseases included in the study are interstitial lung disease, sarcoidosis, chronic obstructive pulmonary disease, and pulmonary hypertension. The purpose of this study is to assess whether patients can tolerate the investigational …
This study investigates myocardial glucose suppression in FDG PET/CT scans. The purpose of this study is to evaluate the effect of sodium-glucose cotransporter-1/2 inhibitors on glucose levels in the heart.The study evaluates the safety and effectiveness of combining a ketogenic diet with an investigational medication to enhance imaging results. Researchers …
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