Found 30 Malignant Adenoma trials
A listing of Malignant Adenoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates how effective one year versus two years of maintenance therapy is for patients with advanced ovarian cancer that has BRCA1/2 mutations or is homologous recombination deficient (HRD+). The purpose is to compare the effects of using the investigational medication, olaparib, with or without an antiangiogenic agent, bevacizumab, …
This study investigates the treatment of KRAS-mutated cancers. The purpose of this study is to evaluate the safety and preliminary effectiveness of a new investigational treatment in patients with specific types of cancer that have a KRAS mutation.The study focuses on assessing the safety and how well the investigational treatment …
This study investigates the effectiveness of an investigational medication combined with ipilimumab in patients with metastatic pancreatic cancer. The purpose is to understand if this combination can slow tumor growth and what side effects may occur. Participants will be placed into two study arms: Arm A will receive the investigational …
This study investigates the effects of an investigational medication combined with nab-paclitaxel and gemcitabine compared to a placebo with the same combination in people with untreated metastatic pancreatic ductal adenocarcinoma (PDAC) who have a specific genetic deletion called homozygous MTAP deletion. The study aims to explore the safety and efficacy …
This study investigates the effectiveness of an investigational medication following surgery and chemotherapy in patients with pancreatic cancer who have specific genetic mutations. The study focuses on patients whose cancer has been surgically removed and who have a mutation in the BRCA1, BRCA2, or PALB2 genes. These genes are known …
This study investigates the effectiveness of adding investigational medication combinations to the usual chemotherapy in patients with HER2 positive endometrial cancer. The investigational medications, which include monoclonal antibodies like trastuzumab and pertuzumab, target HER2 receptors on cancer cells to block signals for growth and potentially mark the cells for destruction …
This study investigates pancreatic cancer. It focuses on a structured lipid medical food designed to address fat malabsorption in patients who have difficulty absorbing fats due to their condition.The purpose of this study is to evaluate the safety, tolerance, and potential effects of the structured lipid medical food. It looks …
This study investigates the effectiveness of adding an investigational medication to the standard treatment for patients with metastatic pancreatic cancer who have specific genetic mutations known as BRCA1 or BRCA2. The purpose of this study is to see if the combination of an investigational medication with olaparib, a targeted therapy …
The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multi-site cohort of individuals with family history of PDAC and/or individuals carrying pathogenic/likely pathogenic germline variants (PGVs) in genes linked …
The purpose of this study is to investigate whether adding investigational medications to standard chemotherapy is effective for treating resectable HER2+ esophagogastric cancer. In this study, patients will receive investigational medications in combination with chemotherapy before surgery to see if this approach can improve treatment outcomes.Participants in this study will …
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