Found 30 Malignant Adenoma trials
A listing of Malignant Adenoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the best way to treat patients with Barrett's esophagus and low-grade dysplasia by comparing two procedures: endoscopic surveillance and endoscopic eradication therapy. Low-grade dysplasia is an early form of abnormal cell growth that may not always progress to cancer. Endoscopic surveillance involves using a camera-equipped tube to …
This study investigates the combination of an investigational medication, administered as telomelysin (OBP-301), with pembrolizumab in patients with advanced or metastatic gastric or gastroesophageal junction cancer. The purpose of this study is to determine if this combination is safe and effective for patients whose cancer has progressed despite previous treatments.Participants …
This study investigates the safety and effectiveness of adding RP2, an investigational treatment, to the standard chemotherapy regimen, FLOT, for patients with stage II or higher, non-metastatic gastroesophageal adenocarcinoma. The purpose of this study is to determine if injecting RP2 directly into the tumors of the stomach and esophagus, combined …
This study investigates the effects of an investigational medication targeting advanced or metastatic solid tumors, including sarcomas. The purpose of this research is to understand how the investigational medication, a recombinant humanized tetravalent antibody, interacts with the human death receptor 5 (DR5). The study aims to explore its potential therapeutic …
To establish novel cell lines from patients with and without Barretts with GERD so we can provide data to support grant proposals to be submitted for NIH funding. N/A N/A
This study investigates the safety and effectiveness of an investigational oral medication designed to degrade SMARCA2 in patients with advanced or metastatic solid tumors that have a SMARCA4 mutation. The purpose of this study is to understand how the investigational medication affects the body, how it is processed by the …
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
This study investigates a maintenance immunotherapy using CD40/Dectin-1 for patients with unresectable pancreatic ductal adenocarcinoma (PDA) who have not shown disease progression after 4-6 months of first-line chemotherapy. This research aims to explore the effectiveness of an investigational immunotherapy in maintaining disease stability in these patients.The study involves several procedures, …
This study investigates the effects of combining an investigational medication with another treatment for patients with metastatic colorectal cancer that primarily affects the liver. In this study, researchers are looking at how the combination treatment works and its safety for patients.Participants in the study will receive the investigational medication along …
This study investigates circulating biomarkers in patients with pancreatic adenocarcinoma. The purpose of this study is to collect blood samples from patients to evaluate these biomarkers, which are substances that can be measured in the blood and may provide information about the cancer.Participants will undergo a procedure to collect blood …
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