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Found 22 Non-Hodgkin's Lymphoma trials

A listing of Non-Hodgkin's Lymphoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Observational
This study investigates the long-term safety of investigational cell therapies in patients who have previously participated in Caribou-sponsored clinical studies, special access programs, or investigator-initiated trials (IITs). The purpose of this study is to observe patients over a period of up to 15 years after they have received their initial …
UPCC 12420 A Phase 2, Open- Label, Single-Arm, Multicohort, Multicenter Trial to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects with Relapsed or Refractory Indolent B-Cell Non-Hodgkin Lymphoma (NHL)
18 years or above
All genders
Phase 2
Interventional
This study investigates the efficacy and safety of an investigational medication in adults with relapsed or refractory indolent B-cell Non-Hodgkin Lymphoma (NHL), specifically follicular lymphoma (FL) and marginal zone lymphoma (MZL). The purpose of this study is to understand how well the investigational medication works in treating these types of …
18 years or above
All genders
Phase 2
Interventional
This study investigates primary central nervous system lymphoma. The purpose of this study is to evaluate the safety and efficacy of an investigational medication as a first-line treatment for individuals who cannot undergo a transplant.The study evaluates the effectiveness and safety of the investigational medication in patients. It focuses on …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and appropriate dosing of investigational cells in patients with T Cell Non-Hodgkin Lymphoma. The purpose of this study is to determine how well these cells can be tolerated by patients and to identify the best dose for future studies. The focus is on patients whose …
18 years or above
All genders
This study investigates providing access to axicabtagene ciloleucel, an investigational medication, for patients who have a disease approved for treatment with this medication but whose product does not meet commercial release criteria. The purpose is to allow patients to receive treatment with axicabtagene ciloleucel that is otherwise unavailable due to …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and efficacy of an investigational medication, surovatamig, administered alone or with other anticancer agents in individuals with mature B-cell malignancies. This study is open-label, meaning both researchers and participants know what treatment is being administered. It includes three substudies, each focusing on different types of …
18 years or above
All genders
Phase 1
Interventional
This study investigates an investigational therapy for treating HIV-associated aggressive B-cell non-Hodgkin lymphoma that has either returned or not responded to previous treatments. The purpose is to evaluate the safety and feasibility of using genetically modified T cells, known as CAR-T therapy, which are designed to target a specific protein …
UPCC 33418 Managed Access Program (MAP) Cohort Treatment Plan CCTL019B2003I to Provide Access for Patients With Out of Specification Leukapheresis Product and/or Out of Specification Manufactured Tisagenlecleucel (CTL019; Kymriah®)
All genders
This study investigates providing access to an investigational medication for patients with serious or life-threatening conditions where standard treatments are not suitable. The study focuses on patients with out-of-specification leukapheresis products or out-of-specification manufactured cells for treatment. Leukapheresis is a procedure that involves removing white blood cells from the body, …
18 years or above
All genders
Phase 4
Interventional
This study investigates the long-term safety and effects of an investigational medication in people with Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), or Non-Hodgkin Lymphoma (NHL) who have already received treatment. The purpose of this study is to provide participants from a previous study with the opportunity to continue …
18 years or above
All genders
Phase 1
Interventional
This study investigates hematologic malignancies. The purpose of this study is to assess the safety and feasibility of using autologous anti-CD45 CAR T cells in combination with CD45 base edited hematopoietic stem and progenitor cells.The study evaluates the effectiveness and safety of these treatments in patients who have relapsed or …
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