Found 22 Non-Hodgkin's Lymphoma trials
A listing of Non-Hodgkin's Lymphoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety, tolerability, and effects of an investigational medication in individuals with blood cancers that have not responded to previous treatments. The purpose of this study is to determine how well the investigational medication works when used alone or in combination with other anticancer agents. Participants will …
This study investigates the safety and anti-cancer activity of an investigational medication in adults with advanced B-cell malignancies. These conditions include Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B-cell Lymphoma (DLBCL), Mantle Cell Lymphoma (MCL), Waldenstrom Macroglobulinemia (WM), Marginal Zone Lymphoma (MZL), Follicular Lymphoma (FL), Primary Central …
This study investigates the use of CAR T cells, a type of cell therapy, in treating patients with CD19+ cancers. The purpose of this study is to understand how safe and feasible it is to use these modified cells in patients whose cancer has come back or has not responded …
This study investigates the safety and tolerability of an investigational medication in patients with advanced solid tumors and lymphomas. The study is divided into two phases: Phase 1 focuses on finding the maximum tolerated dose of the investigational medication, while Phase 2 evaluates its antitumor activity across different types of …
This study investigates the safety and effectiveness of an investigational medication in patients with advanced blood cancers, including Non-Hodgkin Lymphoma, Multiple Myeloma, Acute Myeloid Leukemia, and high-risk Myelodysplastic Syndrome.Participants in the study will receive the investigational medication either alone or in combination with other treatments. The study will monitor the …
This study investigates the safety and feasibility of using investigational cells called huCART19-IL18 in patients with relapsed or refractory CD19+ cancers. These are cancers where the CD19 protein is present on the surface of malignant cells, such as certain types of lymphoma and leukemia. The purpose is to determine if …
This study investigates the use of an investigational therapy for patients who have been diagnosed with a condition approved for treatment with this therapy, but whose therapy does not meet commercial release criteria. The purpose is to provide access to this investigational treatment under specific conditions.Participants in this study will …
This study investigates the use of an investigational medication, a monoclonal antibody targeting Tumor Necrosis Factor Receptor 2 (TNFR2), in people with advanced malignancies. The purpose of the study is to evaluate the safety and tolerability of the investigational medication both alone and in combination with pembrolizumab, a type of …
This study investigates the use of an investigational medication, epcoritamab, before and after CAR-T cell therapy in patients with relapsed or refractory large B-cell lymphomas. This study aims to understand if epcoritamab can improve outcomes when used in conjunction with CAR-T cell therapy, a treatment where a patient's T cells …
The purpose of this study is to investigate the long-term safety of an investigational medication after participants have completed earlier clinical studies. This study will include individuals from previous studies, called originator studies, and will allow them to continue receiving treatment or follow-up visits. The study will use a master …
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