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Found 52 transplant trials
A listing of transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of the funded grant mentioned above is to document the objective psychosocial and quality-of-life (QOL) outcomes of hand transplant compared to other treatment options (e.g. prosthetics, osseointegration, surgical reconstruction) and evaluate these outcomes over time.
This study investigates the use of frailty assessments to predict outcomes for patients aged 60 years and older who are receiving treatments such as chemotherapy, CAR T-cell therapy, or allogeneic stem cell transplant for blood cancers. Frailty assessments help determine a patient's physical resilience and vulnerability, which may influence treatment …
This study investigates the safety and feasibility of using T-cell receptor engineered donor T-cells in patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or acute lymphoblastic leukemia (ALL) who receive transplants from specific types of donors. The …
The purpose of this study is to obtain blood and/or skin tissues from consenting subjects who have been diagnosed with Cutaneous T-cell lymphoma (CTCL), solid organ transplant rejection or GVHD that will be used for current and/or future research. This research may provide information about the causes of these diseases …
This study investigates hematologic malignancies. The purpose of this study is to assess the safety and feasibility of using autologous anti-CD45 CAR T cells in combination with CD45 base edited hematopoietic stem and progenitor cells.The study evaluates the effectiveness and safety of these treatments in patients who have relapsed or …
This is a prospective, multicenter,randomized, nonblinded study to evaluate the safety and effectiveness of the Aortix System versus standard of care medical therapy in patients hospitalized with ADHF and persistent congestion despite usual medical management and who are not being considered for nearterm advanced HF therapy (i.e., LVAD placement or …
The purpose of this study is to improve our understanding of graft-versus-host disease (GVHD) which is a complication that can occur after a bone marrow transplant. Investigators at Mount Sinai and other BMT centers around the world have formed a collaboration to share and study clinical data and blood samples …
The main purpose of this study is to determine if certain genes, hormones, or other factors predict the risk of developing lung vessel disease in patients with liver disease and whether they determine outcome. Patients in need of a liver transplant evaluation or have portopulmonary hypertension or are suspected of …
This study investigates how cancer treatment with immune checkpoint inhibitors (ICI) can lead to the development of autoimmunity. The purpose is to understand the genetic and immune system characteristics that cause some cancer patients to experience immune-related adverse events (irAE) after receiving checkpoint inhibitor therapy.Participants will provide peripheral blood and …
This study investigates treatments for adults newly diagnosed with BCR-ABL-positive Acute Lymphoblastic Leukemia (ALL). The purpose of this study is to compare the effectiveness of a standard treatment involving chemotherapy, steroids, and a type of medicine called a tyrosine kinase inhibitor (TKI) with a treatment that adds another medicine called …
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