Found 52 transplant trials
A listing of transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates a potential treatment for Acute Myeloid Leukemia (AML). The purpose of this study is to explore the use of a modified stem cell transplant combined with engineered T cells, known as chimeric antigen receptor (CAR) T cells, to target and attack leukemia cells. CAR T cells are …
Among lung transplant recipients who survive to 5 years, half suffer from chronic lung allograft dysfunction (CLAD). This study will evaluate how changes in the lung microbiome may cause CLAD in Cystic Fibrosis patients who have been transplanted. This is a case-control study of Cystic Fibrosis lung transplant recipients to …
This study investigates the effects of lower doses of cyclophosphamide, a chemotherapy drug, in patients undergoing bone marrow transplants for certain blood cancers. Blood cancers like leukemia and lymphoma can sometimes be treated with a transplant, but there is a risk that the transplanted cells will attack the recipient's body, …
This study investigates the use of previously cryopreserved ovarian tissue to restore fertility in women who have experienced infertility or ovarian insufficiency after cancer treatments. The purpose of this study is to determine the safety and effectiveness of transplanting this tissue back into the patient's body.Participants in this study will …
To externally validate and refine prediction models for a) incident and b) subsequent KC in a prospective multi-center cohort of kidney and liver transplant recipients, with detailed data on UV exposure, skin type, and photosensitivity.
The purpose of this study is to study how well patients that receive a kidney from an HIV+ organ donor do over 10 years compared to patients that receive a kidney from an HIV- donor. People 18 years of age and older with end-stage renal disease and HIV, and who …
This study investigates the treatment of acute graft-versus-host disease (GVHD).The study evaluates the effectiveness and safety of using ruxolitinib as a treatment for GVHD.Who can participate: Adults aged 18 and older with acute GVHD after allogeneic hematopoietic cell transplant can participate. Participants must not have had prior systemic acute GVHD …
The research study is being conducted to develop a test to predict a common complication after lung transplant called primary graft dysfunction (PGD). Predicting PGD before using donor organs may help reduce deaths and improve outcomes of patients receiving a lung transplant in the future.
This study investigates the use of investigational immunotherapy called Chimeric Antigen Receptor T Cells (CAR T Cells) for patients awaiting kidney transplantation. These patients have a high calculated Panel Reactive Antibody (cPRA) of 99.5% or higher, indicating a likelihood of rejecting most available kidneys. The study aims to determine if …
This study investigates primary central nervous system lymphoma. The purpose of this study is to evaluate the safety and efficacy of an investigational medication as a first-line treatment for individuals who cannot undergo a transplant.The study evaluates the effectiveness and safety of the investigational medication in patients. It focuses on …
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