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Found 42 genetics trials
A listing of genetics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates how cancer treatment with immune checkpoint inhibitors (ICI) can lead to the development of autoimmunity. The purpose is to understand the genetic and immune system characteristics that cause some cancer patients to experience immune-related adverse events (irAE) after receiving checkpoint inhibitor therapy.Participants will provide peripheral blood and …
This study investigates ways to detect prostate cancer earlier in people at genetic risk for aggressive disease, which forms, grows, or spreads quickly. The purpose is to study samples of blood, urine, and tissue in the laboratory to better understand the genetics of prostate cancer. This research aims to identify …
In this secondary use protocol, we will analyze de-identified data from a funded VA study called the Veterans Affairs Multi-omic Platform for Prostate Cancer (VA-MAPP) shared with our team through a fully executed data use agreement with the Greater Los Angeles VA and Penn Medicine to study the genetics of …
The overall objectives of this study are to quantify the proportion of patients who opt in to testing for the genes CDH1 and TP53 on multigene panel testing as well as those who decline testing for these genes, and determine factors that may be predictive of who does and does …
PURPOSE: The objectives of the study are to recruit patients with GI NETs and to develop an annotated database including biosamples for use by our research group including biosamples to facilitate better understanding of the genetics and biochemical signaling pathways leading to tumor formation and malignancy. Our first project is …
This study aims to identify how useful polygenic and integrated risk is in both helping doctors to treat and manage their patients, and identifying people at risk of developing coronary artery disease. Targeted population is previously genotyped individuals in the PMBB. We will calculate an integrated risk score for coronary …
TBD
The purpose of this protocol is to send the pre-collected and shelved DNA samples (parent protocol IRB #376800) from patients fitting the study eligibility requirements for genotyping at the Center for Inherited Disease Research (CIDR) at Johns Hopkins University. The samples will be used in genome-wide association studies (GWAS), which …
This study investigates the genetic risk in young adults with cancer and their relatives. The purpose is to understand how universal genetic testing can identify individuals with a higher risk of cancer who might be missed by traditional testing methods. This study involves young adult cancer patients, aged 18 to …
This study investigates the use of behavioral economics and implementation science to improve the delivery of genomic medicine within a diverse health system. The purpose of this study is to explore how non-geneticist clinicians and patients can be encouraged, through nudges, to utilize genetic testing in situations where it can …
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