Found 21 genetics trials
A listing of genetics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study aims to identify the interplay between behaviors and genes on growth and development among children ages 5 to 7. It assesses the extent to which children's eating, sleep, and physical activity behaviors impacts their weight development over a 1-year period.
The purpose of this research study is to identify biological markers for schizophrenia and bipolar spectrum disorders and related mental illnesses. This information may enable us in the future to develop interventions to improve symptoms and functions or worsening of symptoms.
Create a foundational resource for conducting and sharing ATN imaging and blood biomarker results in the context of the large clinically heterogenous brain-donor-enrolled multi-ADRC cohort. These imaging-plasma sets will be intrinsically linked to cognitive and neurobehavioral data collection, genetics and eventually neuropathology.
This is a 12-month, multicenter, randomized, double-blind, placebo-controlled Phase 3 study to evaluate the safety and efficacy of daily subcutaneous metreleptin treatment in subjects with Familial Partial Lipodystrophy (FPLD). Subjects will be assigned to 1 of 3 groups depending on HbA1c and fasting TGs levels. Participants will complete 10 visits …
Requesting a reliance agreement with an external IRB. The purpose of this double-blind, placebo-controlled trial is to evaluate the safety and efficacy of treatment with plozasiran on the reduction of fasting serum TG from Baseline in subjects with severe hypertriglyceridemia who have fasting TG levels above 500 mg/dL (5.65 mmol/L).
Requesting a reliance agreement with an external IRB. The purpose of this open label extension trial is to evaluate the safety and tolerability of treatment with olezarsen in subjects with severe hypertriglyceridemia who have completed the ISIS 678354-CS5 or -CS6 study with an acceptable safety profile.
Requesting a reliance agreement with an external IRB. The purpose of this double-blind, placebo-controlled trial is to evaluate the safety and efficacy of treatment with plozasiran on the reduction of fasting serum TG from Baseline in subjects with Hypertriglyceridemia who have fasting TG levels between 150 mg/dL and 499 mg/dL.
Requesting a reliance agreement with an external IRB. The primary objective is to evaluate the efficacy of obicetrapib alone for 8 weeks as compared to obicetrapib in combination with Evolocumab for an additional 8 weeks after initial obicetrapib treatment on percent change of Lp(a) levels from Baseline in people with …
Dr. Amit Bar-Or, MD, FRCPC from the University of Pennsylvania Department of Neurology is conducting a study to investigate how the structure and activity of gastrointestinal microbes (bacteria and fungi) found in the gut contribute to multiple sclerosis pathogenesis. You are being asked to participate in this study because either …
PURPOSE The purpose of this research study is to bring together a group of experts in the field of SCA for the purpose of learning more about the disease, finding out how the disease progresses over time, and what may be the best way to measure progression. Also, the study …
