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Found 42 genetics trials

A listing of genetics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years - 99 years
All genders
Observational
This study aims to collect and share Parkinson’s disease genetic testing data from up to 500,000 study participants for research use. Participants will include people with Parkinson's disease (PD). To investigate the genetic link to PD, we will ask participants to contribute their genetic test results and associated raw data …
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Online study
99 years or below
All genders
To collect and store blood samples and genetic data from all patients with PD who receive medical care at the University of Pennsylvania PDMDC to support research needs. To link biospecimens to clinical data in an encrypted database. To encourage collaboration within the University of Pennsylvania and through external collaboration. …
99 years or below
All genders
To collect and store blood samples and genetic data from all patients with PD who receive medical care at the University of Pennsylvania PDMDC to support research needs. To link biospecimens to clinical data in an encrypted database. To encourage collaboration within the University of Pennsylvania and through external collaboration. …
99 years or below
All genders
Subjects with unusual lipids in subjects with known or suspected genetic variants that may be associated with change in lipoprotein kinetics will have two-night, one-day inpatient stay in CHPS, during which they will undergo extensive evaluation of lipoprotein kinetics using stable isotope techniques, OFTT, and OGTT. Subjects will complete a …
Analyses of candidate fluid biomarkers in schizophrenia and bipolar spectrum disorders: Prioritizing mechanisms nominated by genetics
18 years - 50 years
Accepts healthy volunteer
All genders
The purpose of this research study is to identify biological markers for schizophrenia and bipolar spectrum disorders and related mental illnesses. This information may enable us in the future to develop interventions to improve symptoms and functions or worsening of symptoms.
Training to Understand and Navigate Emotions and Interactions
18 years - 99 years
All genders
TUNE In is a social skills program for autistic adults. TUNE In is rooted in cognitive-behavioral therapy (involving greater understanding of your own thoughts, feelings, and behaviors) and mindfulness-based practices (involving greater awareness of yourself and others). The TUNE In curriculum covers skills such as remaining relaxed and aware during …
18 years - 75 years
All genders
The primary objective is to evaluate the efficacy of obicetrapib alone for 8 weeks as compared to obicetrapib in combination with Evolocumab for an additional 8 weeks after initial obicetrapib treatment on percent change of Lp(a) levels from Baseline in people with mild dyslipidemia, defined as Lp(a) levels 50 mg/dL …
18 years - 80 years
All genders
Phase 2
Interventional
This study investigates idiopathic Multicentric Castleman Disease (iMCD).The study evaluates the effects of an investigational medication on iMCD symptoms and how well it is tolerated by participants.Who can participate: Adults aged 18 to 80 with a history of iMCD can participate. Key eligibility includes documented disease history, not responding to …
50 years - 105 years
All genders
Phase 3
Interventional
This study investigates cardiovascular events in individuals with elevated lipoprotein(a).It evaluates the effect of an investigational medication on the risk of heart disease-related death and other major heart events.Who can participate: Adults aged 50 and older with high lipoprotein(a) levels can participate.Study details: Participants will receive either the investigational medication …
99 years or below
All genders
Requesting a reliance agreement with an external IRB. The purpose of this open-label extension trial is to evaluate the long-term safety and efficacy of treatment with plozasiran on the reduction of fasting serum TG from Baseline in subjects with Severe Hypertriglyceridemia.
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