Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Our overall goal is to discover novel breast cancer therapeutics which target the endocrine and paracrine signaling pathways that are essential to tumor development within the tumor microenvironment Please see Section 2 of the full study protocol Please see Section 2 of the full study protocol.
This study investigates the effects of additional treatment after surgery for patients with high-risk well-differentiated pancreatic neuroendocrine tumors. The purpose of this study is to see if giving the investigational medications capecitabine and temozolomide after surgery can prevent or delay the return of cancer compared to just observing the patients …
This study investigates Li-Fraumeni Syndrome (LFS) and Li-Fraumeni-like (LFL) Syndrome, focusing on the increased cancer risk associated with changes in the TP53 gene. The purpose of this study is to collect and analyze clinical data and biological samples from patients with these conditions to better understand the relationship between genetic …
This study will: -- Collect tissue and body fluid specimens for immediate analysis and short-term storage while protecting the confidentiality of individuals undergoing resection of soft tissue sarcoma and GIST -- Correlate relevant clinical characteristics for the identification of significant tumor and immune cell markers that may have impact on …
This study investigates the impact of a decision aid on colorectal cancer screening behaviors among older adults with low health literacy. The purpose of this study is to see if a newly developed decision aid pamphlet can influence the screening intentions of adults aged 75-85, who may have different risk …
This study investigates treatment options for patients with advanced or metastatic colorectal cancer that is resistant to standard therapies. The purpose is to compare two treatments: one with a combination of two investigational medications and another with one investigational medication alone. The cancer can spread to other parts of the …
This study investigates the use of circulating free-DNA (cfDNA) markers in blood to improve detection of colorectal cancer (CRC) and advanced adenomas. The purpose of this study is to collect blood samples and clinical data from participants in order to optimize a biomarker panel for better detection of these conditions.Participants …
This study investigates the long-term safety and efficacy of gene-modified T-cell therapy in both children and adults. The purpose is to observe participants who have previously received this therapy in a Celgene or Celgene alliance partner study.Participants will be monitored over time to assess the effects of the gene-modified T …
The purpose of this study is to investigate the effects of immune checkpoint inhibitors (ICI) on the heart and circulatory system in patients with breast cancer or non-small cell lung cancer. This study focuses on understanding how these medications, which are used in cancer treatment, might impact heart health. An …
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
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