Found 57 ne-neurology trials
A listing of ne-neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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To evaluate the clinical efficacy of VIM0423 compared to placebo in individuals with isolated dystonia.
This is a study evaluating Vtx-002 as a potential treatment for ALS. TDP-43 is a protein that is often dysregulated in ALS patients. Vtx-002 is designed to reduce pathological groups of TDP-43, reducing and preventing ALS pathology. Patients will receive a 1 time dose of Vtx-002 and then undergo a …
This is a phase III, double-blind, placebo-controlled study to evaluate the efficacy and safety or NI0752 in participants with Progressive Supranuclear Palsy (PSP). Participants will receive either 50mg of NI0752 or placebo every 12 weeks for 72 weeks via intrathecal injection during the double-blind period followed by an OLE period.
This is a study evaluating SAR446268 as a treatment for DM1. SAR446268 is designed to deliver miRNA to pathological DMPK gene expression that leads to DM1. Patients will receive a 1-time dose of the study drug and then undergo a 5 year follow-up period to monitor safety and efficacy.
To assess the effect of donanemab versus placebo on cognitive and functional progression in participants with established alpha-synuclein and amyloid co-pathology
Clarity is a Phase 3 double-blind, placebo controlled, randomized clinical trial in patients with non-cardioembolic ischemic stroke or high-risk TIA, to determine if the addition of cilostazol to standard-of-care aspirin or clopidogrel reduces major adverse cardiovascular events during long term follow-up
The study is at the Penn Memory Center at the University of Pennsylvania and is under the direction of David Wolk, M.D.. We are currently recruiting normal control participants ages 75 years and older. The purpose of this study is to collect, store and analyze cognitive data and biological samples, …
Dr. Amit Bar-Or, MD, FRCPC from the University of Pennsylvania Department of Neurology is conducting a study to investigate how the structure and activity of gastrointestinal microbes (bacteria and fungi) found in the gut contribute to multiple sclerosis pathogenesis. You are being asked to participate in this study because either …
A novel device, developed at the University of Pennsylvania, utilizes diffuse correlation spectroscopy (DCS), which allows for real-time, continuous bedside monitoring of CBF using near infrared light. This non-invasive device holds great promise for monitoring cerebral hemodynamics in stroke patients. Prior work from our group has used this device to …
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