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Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Determine interrater reliability between 3D whole body image assessment and in-person clinical assessment regarding the need for in-person evaluation of keratinocyte carcinomas in high-risk patients. VectraWB360 3D whole-body photography-based assessment by a dermatologist (Approach 1). In-person clinical assessment by a dermatologist (Approach 2). Determine interrater reliability between 3D whole body …
The aim of the study is to collect relevant pregnancy outcome data, medical history, and blood samples from pregnant women carrying a singleton fetus undergoing non-invasive screening for early, preterm and term pre-eclampsia (PE) starting at 11 weeks 0 days to 14 weeks 0 days gestation in support of validating …
The study is a prospective, open-label, multicenter, extension study of acoramidis in participants with newly diagnosed ATTR-CM (or both ATTR-CM and ATTR-PN). The study population will be participants from the AG10-501 study only who are newly diagnosed with ATTR-CM (or both ATTR-CM and ATTR-PN) during that study. Participants will be …
The objectives of this proposal are to: 1) describe the incidence of depression and trajectory of depressive symptoms; 2) identify potential determinants of depression; and 3) characterize the consequences of depression in a large, international cohort of patients with PC and in subgroups of this population during early and late …
This study investigates the use of an investigational medication in combination with standard therapies for patients with acute myeloid leukemia (AML) who have specific genetic mutations and have not yet received treatment. The purpose of this study is to assess the benefits and risks of adding the investigational medication to …
This study investigates early-stage triple-negative breast cancer (TNBC) and the effects of observation versus continued immunotherapy after achieving a complete response to initial treatments. The study aims to determine if observation alone can provide similar outcomes to further treatment with an investigational medication after surgery.Participants will be divided into two …
Please refer to Protocol Section 3 (Study Objectives). Please refer to Protocol Section 3 (Study Objectives). Please refer to Protocol Section 3 (Study Objectives).
This study investigates the safety and effectiveness of two investigational medications in treating HER2-negative metastatic breast cancer. The study involves two investigational medications given in sequence, either trastuzumab deruxtecan followed by datopotamab deruxtecan or vice versa, to understand if this approach works for patients who have already tried other similar …
The NCI SHIP multi-site trial will recruit 100 individuals at Penn scheduled to undergo colposcopy to 1) evaluate self- and clinician-collected test primary HPV test accuracy by calculating clinical sensitivity and specificity for detection of CIN2+n histopathology; and 2) positive and negative percent agreement between self- and clinician-collected HPV samples.
This study investigates the use of investigational cells called CART-EGFR-IL13Ra2 in patients with recurrent glioblastoma, a type of brain cancer. The study aims to evaluate the safety and effectiveness of these cells in patients whose cancer has returned after previous treatment.Participants will receive CART-EGFR-IL13Ra2 cells along with chemotherapy or before …
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