Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of an investigational medication in combination with standard therapies for patients with acute myeloid leukemia (AML) who have specific genetic mutations and have not yet received treatment. The purpose of this study is to assess the benefits and risks of adding the investigational medication to …
This study investigates early-stage triple-negative breast cancer (TNBC) and the effects of observation versus continued immunotherapy after achieving a complete response to initial treatments. The study aims to determine if observation alone can provide similar outcomes to further treatment with an investigational medication after surgery.Participants will be divided into two …
Please refer to Protocol Section 3 (Study Objectives). Please refer to Protocol Section 3 (Study Objectives). Please refer to Protocol Section 3 (Study Objectives).
This study investigates the safety and effectiveness of two investigational medications in treating HER2-negative metastatic breast cancer. The study involves two investigational medications given in sequence, either trastuzumab deruxtecan followed by datopotamab deruxtecan or vice versa, to understand if this approach works for patients who have already tried other similar …
The NCI SHIP multi-site trial will recruit 100 individuals at Penn scheduled to undergo colposcopy to 1) evaluate self- and clinician-collected test primary HPV test accuracy by calculating clinical sensitivity and specificity for detection of CIN2+n histopathology; and 2) positive and negative percent agreement between self- and clinician-collected HPV samples.
This study investigates the use of investigational cells called CART-EGFR-IL13Ra2 in patients with recurrent glioblastoma, a type of brain cancer. The study aims to evaluate the safety and effectiveness of these cells in patients whose cancer has returned after previous treatment.Participants will receive CART-EGFR-IL13Ra2 cells along with chemotherapy or before …
This study investigates a maintenance immunotherapy using CD40/Dectin-1 for patients with unresectable pancreatic ductal adenocarcinoma (PDA) who have not shown disease progression after 4-6 months of first-line chemotherapy. This research aims to explore the effectiveness of an investigational immunotherapy in maintaining disease stability in these patients.The study involves several procedures, …
This study investigates the effects of photobiomodulation therapy (PBMT) on chronic lymphedema in survivors of head and neck cancer. PBMT is a type of light therapy that has been approved by the U.S. Food and Drug Administration for treating arm lymphedema related to breast cancer. This study aims to confirm …
A5385 is a two-step non-interventional study for participants from qualifying ACTG and non-ACTG interventional cure trials (parent studies) that include an analytical treatment interruption (ATI) period who achieved prolonged viral control off antiretroviral therapy (ART) post-intervention (post-intervention control [PIC]) in their parent study.
Featured study
This study is a biorepository that collects and stores ocular fluid specimens obtained during routine ophthalmic procedures. The purpose of the biorepository is to support future research aimed at understanding ocular diseases, identifying biomarkers, and improving diagnostic or therapeutic approaches. No extra procedures are performed for research purposes: only small …
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