Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes. It focuses on understanding the effects of an investigational medication called AUTX-703.The study evaluates the safety, tolerability, and how the body processes and responds to AUTX-703. It looks at how effective the investigational medication is in treating the conditions.Who can …
Determine the safety of short-course palliative RT for pediatric patients with incurable CNS disease, defined as the ability to successfully complete short-course RT without grade 3 or higher toxicity (per CTCAE v5) within 3 months of the final fraction of RT. Determine the effects of short course RT on patient …
This study investigates digital mindfulness-based interventions for younger breast cancer survivors who experience elevated depressive symptoms. The purpose of this study is to compare two different digital approaches: one that is live and instructor-led via Zoom, and another that is self-paced and app-based. Participants are breast cancer survivors diagnosed at …
The purpose of the study is to evaluate the safety and efficacy of dual chamber personalized pacing compared to minimal or no pacing for the treatment of HFpEF. This study will evaluate a personalized cardiac pacing rate as a treatment for symptomatic heart failure with preserved ejection fraction (LVEF ≥50%).
The present trial will evaluate safety, efficacy, PK, and immunogenicity of repeat dosing of spesolimab 900 mg i.v. vs. placebo, both in combination with oral corticosteroid (20 mg/day prednisone or prednisolone, which will be tapered off by Week 8) in trial participants with ulcerative PG.
This study investigates a targeted palliative care program for individuals with metastatic breast cancer and their caregivers. The aim of this study is to enhance communication between patients, caregivers, and clinicians about the patients' goals and preferences for care.Participants in the study will be randomly assigned to receive either the …
Determine interrater reliability between 3D whole body image assessment and in-person clinical assessment regarding the need for in-person evaluation of keratinocyte carcinomas in high-risk patients. VectraWB360 3D whole-body photography-based assessment by a dermatologist (Approach 1). In-person clinical assessment by a dermatologist (Approach 2). Determine interrater reliability between 3D whole body …
The aim of the study is to collect relevant pregnancy outcome data, medical history, and blood samples from pregnant women carrying a singleton fetus undergoing non-invasive screening for early, preterm and term pre-eclampsia (PE) starting at 11 weeks 0 days to 14 weeks 0 days gestation in support of validating …
The study is a prospective, open-label, multicenter, extension study of acoramidis in participants with newly diagnosed ATTR-CM (or both ATTR-CM and ATTR-PN). The study population will be participants from the AG10-501 study only who are newly diagnosed with ATTR-CM (or both ATTR-CM and ATTR-PN) during that study. Participants will be …
The objectives of this proposal are to: 1) describe the incidence of depression and trajectory of depressive symptoms; 2) identify potential determinants of depression; and 3) characterize the consequences of depression in a large, international cohort of patients with PC and in subgroups of this population during early and late …
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