Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Study of Investigational Medication in Patients with Advanced Cancers that Form in Organs or Tissues
This study investigates an investigational medication in patients with advanced or metastatic solid tumors. The purpose of the study is to evaluate the safety, tolerability, and dose-limiting toxicities (DLTs) of the investigational medication. The study will also determine the maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE) in …
This study investigates the use of an investigational medication in comparison to primary surgery for individuals with early stage Cutaneous Squamous Cell Carcinoma (CSCC). This study aims to understand how the investigational medication affects the tumor and the body, as well as the potential side effects that may occur.Participants in …
This study investigates metastatic castration-resistant prostate cancer (mCRPC). The purpose of this study is to compare the effectiveness of an investigational medication, ifinatamab deruxtecan, against standard chemotherapy in extending the lives of participants and delaying cancer progression.Participants in the study will receive either the investigational medication or chemotherapy. The study …
This study investigates the effect of adding radiation therapy to the usual treatment for patients with high-risk asymptomatic bone metastases. These metastases are defined by their location or size, such as those that are 2 cm or larger or located in critical areas like the hip, shoulder, or spine, and …
This is an open-label, single arm, multicenter extension study for participants with established CVD and elevated Lp(a) who completed the parent study. The purpose of this study is to assess the long-term safety and tolerability of pelacarsen (TQJ230). The study consists of: Screening period (up to approximately 30 days) and …
This study investigates an imaging technique using an investigational medication and a special camera system to detect cancer in patients undergoing surgery for endometrial cancer. The purpose of this study is to assess how well the investigational medication works when used with this imaging technique during surgery.Participants will undergo several …
This study investigates the effects of an investigational medication combined with nab-paclitaxel and gemcitabine compared to a placebo with the same combination in people with untreated metastatic pancreatic ductal adenocarcinoma (PDAC) who have a specific genetic deletion called homozygous MTAP deletion. The study aims to explore the safety and efficacy …
This study investigates the effectiveness of letrozole, an investigational medication, in comparison to a placebo for postmenopausal women with hormone receptor-positive breast cancer. The purpose of this study is to determine if taking letrozole for five years can improve disease-free survival after completing five years of hormonal therapy, which may …
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
Primary Objective To assess whether B.brilliant, a Novel Digital Breast Tomosynthesis System leads to better visualization of calcifications compared to standard wide-angle DBT imaging Secondary Objectives To evaluate the accuracy of NDBT B.brilliant for predicting the number of calcifications and extent of the calcification cluster(s) and morphology compared to standard …
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