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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

UPCC 26424: An Analysis of Manufacturing Outcomes with Patient Factors from Multiple Myeloma Patients Prescribed Ciltacabtagene Autoleucel

99 years and younger
All genders
The purpose of this study is to learn how participant factors (such as medical history and manufacturing starting material, also known as Apheresis) can predict successful manufacturing of ciltacabtagene autoleucel (Cilta-cel). This information can be used to potentially improve manufacturing processes and treat more patients with Cilta-cel. We would like …
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UPCC 03524: A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination with Carboplatin plus Pemetrexed Versus Platinum plus Pemetrexed or Nivolumab plus Ipilimumab in Participants with Unresectable Pleural

99 years and younger
All genders
This is a phase III, randomized, open-label, multicenter, global study to determine the efficacy and safety of Volrustomig (MEDI5752) + Carboplatin + Pemetrexed vs the investigator's choice of platinum + Pemetrexed or Nivolumab + Ipilimumab in participants with unresectable pleural mesothelioma. We would like to rely on WCG IRB as …
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UPCC 12124: A Phase III, Open-label, Randomised Study of Neoadjuvant Datopotamab Deruxtecan (Dato-DXd) Plus Durvalumab Followed by Adjuvant Durvalumab With or Without Chemotherapy Versus Neoadjuvant Pembrolizumab Plus Chemotherapy Followed by Adjuvant

99 years and younger
All genders
This is a Phase III, 2-arm, randomised, open-label study assessing the efficacy and safety of neoadjuvant Dato-DXd plus durvalumab followed by adjuvant durvalumab with or without chemotherapy compared with neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab with or without chemotherapy in participants with previously untreated TNBC or hormone receptor-low/HER2-negative …
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ALATHEA

99 years and younger
All genders
To evaluate the effects of VLX-1005 compared to placebo on platelet count recovery, an important clinical outcome in patients with positive serotonin release assay (SRA+) confirmed HIT, on a background of standard of care (SoC) anticoagulation -To evaluate the effects of VLX-1005 compared to placebo on platelet count recovery, an …
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XLRS

99 years and younger
All genders
ATSN-201 is a gene therapy designed to introduce the functional hRS1 gene to photoreceptors in the eye via subretinal admin using a novel rAAV vector, thereby restoring or attenuating the deterioration of vision in patients with XLRS. Subretinally administered AAV vector-mediated gene augmentation therapy has been shown to be safe …
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COAST

99 years and younger
All genders
This randomized clinical trial seeks to compare the efficacy and safety of standard versus low energy primary SLT in eyes with ocular hypertension or mild-moderate open-angle glaucoma, and to determine the optimal interval and energy for repeat SLT (as needed at initially-assigned energy versus annually at low energy)
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PBL-0405-01

99 years and younger
All genders
Please refer to section 3 of the protocol document. Please refer to section 3.1 of the protocol document. Please refer to section 3.2 of the protocol document.
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LeMi EPL Protocol

99 years and younger
All genders
Objective 1: Estimate efficacy of medical management with oral letrozole 10 mg daily for three consecutive days followed by vaginal misoprostol 800 mcg for treatment of EPL Objective 2: Assess side effects, adverse events, and patient acceptability associated with letrozole and misoprostol for medical management of EPL Our primary outcome …
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NGT Pilot Study

99 years and younger
All genders
PURPOSE To perform a pivotal study of the next-generation tomosynthesis system with volunteers recruited among women with suspicious breast finding(s), with the goal of assessing the effect of scanning method on characterization of findings as benign or malignant. The primary outcome variable for this 3D mammography imaging study is the …
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UPCC 03424 Phase IIa Trial to Evaluate Epcoritamab Administered Before and After CAR-T Cell Therapy in Patients with Relapsed or Refractory Large B-cell Lymphomas

99 years and younger
All genders
Please refer to Protocol Section 2 (Study Objectives and Endpoints). Please refer to Protocol Section 2 (Study Objectives and Endpoints) and Protocol Section 9.4 (Primary and Secondary Endpoints). Please refer to Protocol Section 2 (Study Objectives and Endpoints) and Protocol Section 9.4 (Primary and Secondary Endpoints).
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