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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Kidney Hypoxia

99 years and younger
All genders
The objective of the proposed study is to determine the sensitivity of the new method to detect expected changes in rMRO2 from breathing air containing 21% oxygen versus air containing less oxygen (akin to changes seen at high altitudes). The effect of hypoxia on rMRO2 mimics the hypoxic state the …
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EAY191-N4: A Randomized Trial of Selumetinib and Olaparib or Selumetinib alone in Patients with recurrent or persistent RAS Pathway Mutant Ovarian and Endometrial Cancers: A ComboMATCH Treatment Trial

99 years and younger
All genders
Cohort 1:Compare progression free survival of combination of olaparib and selumetinib to selumetinib alone in patients with RAS mutant ovarian cancer. Cohort 2:Compare progression free survival of combination of olaparib and selumetinib to selumetinib alone in patients with RAS mutant endometrial cancer.
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Eye90 Microspheres

99 years and younger
All genders
Evaluate the effectiveness of Eye90 treatment in subjects with unresectable HCC. Incidence of adverse events (AEs), grouped by System Organ Class (SOC) and Preferred Term (PT), relatedness to study treatment/procedure, and severity. Incidence of serious adverse events (SAEs), grouped by System Organ Class (SOC) and Preferred Term (PT), relatedness to …
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COLT

99 years and younger
All genders
We are requesting a reliance agreement with the University of Washington Human Subjects Division. The purpose of this study is to determine the safety and efficacy of two doses of CMV-MVA Triplex vaccine pre-transplant. The target population is CMV seronegative prospective liver transplant recipients. The main study interventions are pre-transplant …
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Phase III Vitiligo Study

99 years and younger
All genders
The research study is being conducted to look at the efficacy of SCENESSE® (also known as afamelanotide) combined with narrow-band ultraviolet B (NB-UVB) light in participants with nonsegmental vitiligo. Procedures: vital signs, physical examination, medical history, blood and urine tests, past and current medications, full body photography, NB-UVB light treatment, …
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NOTCH Study

99 years and younger
All genders
Notch signaling plays a key role in regulating stem cell differentiation in the GI tract, with increased Notch activity promoting absorptive lineage differentiation, and Notch inhibition resulting in secretory lineage differentiation including goblet cells, the hallmark of esophageal intestinal metaplasia. Notch may be particularly relevant to BE and progression to …
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FDG and SGLT2 Glucose Suppression

99 years and younger
All genders
Primary objective is to: To assess rates of complete myocardial glucose suppression (MGS) with 7 days of sotagliflozin 400 mg QD among healthy volunteers on a background of 1 day of the KD (N=20) and 3 days of the KD (N=20). Secondary objective is to: To investigate the relationship between …
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Delphi-MD TMS EEG TBI Study

99 years and younger
All genders
To assess TMS-EEG abilities to aid in diagnosis, prognosis, and classification of TBI patients and predictions of clinical outcomes as well as to assess Delphi-MD abilities in the classification of TBI injury in comparison to standard brain measures. Differentiating between healthy controls and TBI participants in measured outputs of the …
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PrEP Implementation for Black Primary Care Patients

99 years and younger
All genders
The overarching goal of this proposal is to facilitate Dr. Watsons long-term goal to become an independent investigator focused on the development of implementation strategies to achieve equitable HIV prevention outcomes among Black populations. The results of this study will be important for the field of implementation science as it …
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UPCC 13824: A Phase 2, Randomized, Double-blind, Clinical Study of V940 (mRNA-4157) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in the Adjuvant Treatment of Participants With Renal Cell Carcinoma

99 years and younger
All genders
The primary objective of the study is to compare V940 plus pembrolizumab to placebo plus pembrolizumab with respect to disease-free survival (DFS) as assessed by the investigator. The primary hypothesis is that V940 plus pembrolizumab is superior to placebo plus pembrolizumab with respect to DFS. We would like to rely …
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