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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

UPCC 05423 A Phase I, Open-Label, Dose Escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of ONO-7018 in Patients with Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) or Chronic Lymphocytic Leuk

99 years and younger
All genders
Please refer to Protocol Section 3 (Objectives and Endpoints). Please refer to Protocol Section 3 (Objectives and Endpoints). Please refer to Protocol Section 3 (Objectives and Endpoints).
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S2104: A Phase II Randomized Trial of Postoperative Adjuvant Capecitabine and Temozolimide versus Observation in High-Risk Pancreatic Neuroendocrine

99 years and younger
All genders
The purpose of this study is to compare the usual approach (observation) to using capecitabine and temozolomide. We will enroll patients with High-Risk Pancreatic Neuroendocrine Tumors. We will utilize CIRB as the IRB of Record.
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INDICT

99 years and younger
All genders
To determine whether treatment guided by electrocorticographic monitoring of spreading depolarizations improves outcomes in patients who require surgery for severe TBI in the neuro intensive unit.
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UPCC 04424 A Phase 1 FirstinHuman Study Evaluating Safety, Pharmacokinetics, and Efficacy of ABBV787 in Adult Subjects with Acute Myeloid Leukemia (AML)

99 years and younger
All genders
Please refer to Protocol Section1.1.1 (Objectives and Endpoints). Please refer to Protocol Section1.1.1 (Objectives and Endpoints). Please refer to Protocol Section1.1.1 (Objectives and Endpoints).
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CCN020 Ovaprene

99 years and younger
All genders
The Ovaprene® Contraceptive is a monthly nonhormonal intravaginal contraceptive indicated for the prevention of pregnancy in women of reproductive age. This single arm open-label study intends to enroll approximately 656 sexually active women at risk for pregnancy to conduct the pivotol effectiveness study. Participants will use Ovaprene as their sole …
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BDPI-20-004

99 years and younger
All genders
For a detailed list of objectives, please refer to Section 3, "Objectives" in the latest protocol. For a detailed list of primary outcomes, please refer to the Section 3.1, "Primary Endpoints" in the latest protocol. For detailed list of secondary outcomes, please refer to Section 3.2, " Secondary Endpoints" in …
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CT evaluation of carotid plaque components

99 years and younger
All genders
Specific Aim 1: To validate the diagnostic performance of photon counting/spectral CT to distinguish plaque tissue components in patients with ischemic stroke/transient ischemic attack (TIA) and are treated medically against (1) carotid MRI and (2) plaque segmentation software of the PCCTA images. Specific Aim 2: To validate the diagnostic performance …
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Intraoperative Echocardiography in Low-Risk CABG Surgery

99 years and younger
All genders
The goal of this pilot RCT is to assess the real-world feasibility of undertaking a trial that will randomize isolated CABG surgery patients to default (i.e. obligatory) as-needed (i.e. backup) intraoperative TEE. Trial outcomes will include subject recruitment, feasibility of intervention, incidence gastroesophageal dysfunction, and cardiac surgeon satisfaction with intraoperative …
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CAB-101: A phase 1, open-label, safety and dosing study of autologous desmoglein 3 chimeric autoantibody receptor T cells (DSG3-CAART) in subjects with active, anti-DSG3, mucosal-dominant pemphigus vulgaris

99 years and younger
All genders
This research is being done to determine the maximum dose of an investigational drug called autologous desmoglein 3 chimeric autoantibody receptor T cells (DSG3-CAART) that can be safely given to patients with pemphigus vulgaris to target and kill only the B cells that are making the autoantibodies that attack DSG3.
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ACCCESS

99 years and younger
All genders
The overall objective of this study is to evaluate the safety and effectiveness of the Genio® System in treating patients diagnosed with moderate to severe obstructive sleep apnea (OSA) who are intolerant of/failed/refused PAP treatments and present with complete concentric collapse (CCC) at the soft palate level (velopharynx) as diagnosed …
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