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Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates Li-Fraumeni Syndrome (LFS) and Li-Fraumeni-like (LFL) Syndrome, focusing on the increased cancer risk associated with changes in the TP53 gene. The purpose of this study is to collect and analyze clinical data and biological samples from patients with these conditions to better understand the relationship between genetic …
Please refer to Section 6 of the full protocol (Study Objectives). Please refer to Section 13 of the full protocol (Statistical Analysis). Please refer to Section 13 of the full protocol (Statistical Analysis).
See Section 2.1 See section 5.1 See section 5.1
Our overall goal is to discover novel breast cancer therapeutics which target the endocrine and paracrine signaling pathways that are essential to tumor development within the tumor microenvironment Please see Section 2 of the full study protocol Please see Section 2 of the full study protocol.
The objective of this study is to identify families and individuals with tumors and characterize inherited genetic variation. The outcome of the study is the identification of novel high and low penetrance cancer susceptibility alleles. This is expected to significantly advance our knowledge of the development of cancer and has …
To investigate the possible re-activation of CAR T-cells in response to interventions subsequent to CAR T-cell infusion.
The purpose of this study is to investigate the cancer risks linked to CTNNA1 gene alterations. CTNNA1 gene changes, known as loss-of-function variants, may increase the risk for certain hereditary cancers such as gastric and breast cancer. This study will collect personal and family history from individuals with these gene …
To investigate immunologic changes in Hodgkin Lymphoma patients treated with itacitinib (a JAK inhibitor) in combination with everolimus (an mTOR inhibitor).
To create a comprehensive system to collect, catalogue, and store biological specimens (tumor samples) from subjects with confirmed or suspected pancreatic cancer for future research use. To generate "tumor organoids" from these biopsy or surgical specimens. To integrate the specimen collections with clinical data to permit the most informative clinical- …
This study investigates the genetic risk in young adults with cancer and their relatives. The purpose is to understand how universal genetic testing can identify individuals with a higher risk of cancer who might be missed by traditional testing methods. This study involves young adult cancer patients, aged 18 to …
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