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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

ICE-OSA

99 years and younger
All genders
The primary objectives of this study are to establish if there is a relationship between successful treatment of OSA with the Cryosa Procedure and baseline quantity of oropharyngeal fat, baseline pharyngeal opening pressure (PhOP), and baseline tongue position and tongue motion. Secondary objectives of this study include assessing whether quantity …
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LTCC to Improve Surgical Outcomes

99 years and younger
All genders
We are requesting a reliance agreement with an external IRB (Duke University). The purpose is to refine the Lung Transplant (LTx) Textbook Outcome (TO) definition using retrospective clinical data and to build a machine learning algorithm to predict failure to achieve the refined TO for LTx. A retrospective cohort will …
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Aqueous Humor Proteomics

99 years and younger
All genders
PURPOSE The goal of this study is to measure the levels of over 11,000 proteins in the aqueous humor and correlate it with single-cell transcriptomics data. This will improve understanding of the molecular mechanisms and cell types contributing to dry AMD, POAG, and Stargardts disease. This will allow us to …
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EA5221: A Randomized Phase III Trial of Chemo-Immunotherapy vs Immunotherapy Alone for the Vulnerable Older Adult with Advanced Non-Small Cell Lung Cancer: The ACHIEVE Study

99 years and younger
All genders
This study aims to provide much-needed data regarding how to optimally treat vulnerable older adults with metastatic NSCLC.
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ARGX-117-2202

99 years and younger
All genders
A non-interventional registry study for adult patients diagnosed with Multifocal Motor Neuropathy seeking to document diagnosis, disease progression, treatment, outcomes and laboratory values from blood sampling.
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A071401 Phase II Trial of SMO/AKT/NF2/CDK Inhibitors in Progressive Meningiomas with SMO/AKT/NF2/CDK Pathway Mutations

99 years and younger
All genders
To determine the activity of a SMO inhibitor in patients with meningiomas harboring SMO and PTCH1 mutations as measured by 6-month PFS and response rate.
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Sanofi

99 years and younger
All genders
The dupilumab clinical program in EoE has provided evidence that long-term suppression of IL-4 and IL-13 could lead to progressive improvement in fibrostenosis. . There is a need for longer term assessments with comprehensive functional, histological, molecular, clinical, and endoscopic assessments to characterize the risk of fibrotic progression as well …
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SOL-MDD-301

99 years and younger
All genders
The purpose of this research study is to determine whether the study drug, Solriamfetol, is safe and effective for the treatment of Major Depressive Disorder (MDD). Solriamfetol, also called Sunosi®, is approved by the European Medicines Agency (EMA) and the United States Food and Drug Administration (FDA) for people who …
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UPCC 25223: A Phase I/II Open-Label Study to Evaluate the Safety, Cellular Kinetics and Efficacy of AZD5851, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against GPC3 in Adult Participants with Advanced/Recurrent HEpatocellular CarciNomA

99 years and younger
All genders
Please refer to Protocol Section 3 (Objectives, Endpoints, and Estimands). Please refer to Protocol Section 3 (Objectives, Endpoints, and Estimands). Please refer to Protocol Section 3 (Objectives, Endpoints, and Estimands).
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A phase 3, randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to first-line corticosteroids in primary immune thrombocytopenia

99 years and younger
All genders
To demonstrate that the addition of ianalumab to standard first-line corticosteroids prolongs Time to Treatment Failure compared to Corticosteroids alone in participants with primary ITP. ITP means immune thrombocytopenia. Time from randomization to treatment failure which is defined as Platelet count below 30G/L after 8 weeks from randomization. Need for …
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