A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The incidence of kidney stone disease, especially among children, has risen rapidly. The goal of this study is to determine how what you eat and drink (your diet), antibiotics you take, and the bacteria that live in your gut (microbiome) contribute to developing kidney stones.
The purpose of this study is to partner with patients to understand how to best treat the mental health and substance use needs of individuals living with HIV who receive care at Penn Medicine. Participating in this study involves a one-time interview. During the interview, a researcher will ask you …
The 5-year K01 Mentored Research Scientist proposal will employ brain, neurocognitive, and computational tools (e.g., machine learning) to understand the impact of opioid-use disorder (OUD) and common co-occurring issues on executive function and clinical outcomes.
The purpose of this study is to evaluate the safety, recommended dose, antitumor activity, and pharmacokinetics of JCAR017 in subjects with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma. The safety of JCAR017 in subjects who are receiving concurrent ibrutinib will also be evaluated.
Establish a scalable reference library of anatomical 3D maps of the thoracic duct in healthy individuals Map lymphatic vessel 3D molecular maps of the tissue sample obtained during thoracic duct-venous re-anastomosis surgery to 3D cross-sectional (MR and/or CT) imaging of the region of interest 3. Coordinate with the HuBMAP Consortium …
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Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C HY-2-15 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C HY-2-15 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
The study will assess the safety, PK, PD, and preliminary efficacy of ABBV-CLS-484 as monotherapy and in combination with a PD-1 targeting agent or with a or a vascular endothelial growth factor receptor tyrosine kinase inhibitor. The trial aims to establish a safe, tolerable, and efficacious dose of ABBV-CLS-484 as …
The primary aim is to conduct a multicenter international randomized control trial to test the hypothesis that the use of a two or more AGs compared to a single arterial graft is associated with a reduction in the composite outcome of death from any cause, any stroke, post discharge myocardial …
This study is available to subjects who have previously agreed to receive lisocabtagene maraleucel. The lisocabtagene maraleucel T cells for those subjects that were produced do not meet all of the prespecified release criteria to be used as a routine prescription drug as required by the governing health authority-- this …