Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and tolerability of genetically modified autologous T cells in patients with recurrent or refractory solid tumors. The T cells are engineered to express a receptor that recognizes a specific cancer-related protein called PRAME, which is often found in melanoma and other solid tumors. The study …
The goal of RECIPE (Recruitment and Engagement in Care to Impact Practice Enhancement) for Sickle Cell Disease is to find unaffiliated patients with SCD using three distinct pathways, engage them in care using linkage coordinators and understand the contextual factors and implementation support needed to ensure these methodologies can be …
This study investigates the effects of total ablative therapy compared to usual systemic therapy in patients with limited metastatic colorectal cancer. Colorectal cancer can spread to other parts of the body, and this study focuses on cases where it has spread to up to four sites. Ablative therapy aims to …
This study investigates the safety of an investigational treatment using allogeneic T stem cell memory (Tscm) CAR-T cells in patients with relapsed or refractory Multiple Myeloma (RRMM). The study involves different parts, including dose escalation to find a safe dose and fixed-dose administration to see how the treatment works.Participants will …
This study investigates the effectiveness of two different radiation therapy approaches, fractionated stereotactic radiosurgery (FSRS) and single fraction stereotactic radiosurgery (SRS), in treating patients with cancer that has spread to the brain. SRS involves delivering a single large dose of radiation to the tumor, while FSRS spreads the dose over …
CHAP Child is a follow-up study to the CHAP Randomized Trial. The study will follow up the children born to CHAP Trial participants with a target follow up age of 7 years and older. This protocol seeks to define the long-term safety of routine prenatal pharmacologic treatment of mild CHTN …
This study investigates an investigational medication for women with advanced platinum-resistant epithelial ovarian cancer, including primary peritoneal and fallopian tube cancers. The purpose of this study is to evaluate the safety and effectiveness of the investigational medication in treating these types of cancers, which are known for being difficult to …
This study investigates the safety and efficacy of an investigational medication for patients who require treatment with a product that does not meet commercial release standards but is deemed safe for use in clinical settings. The purpose of this study is to provide access to this investigational medication for patients …
The TMD-PRIME study will be a repository for DNA, RNA, plasma, serum, bone, & tissue from patients enrolled at the Penn Center for Temporomandibular Joint Disease (TMD). TMD-PRIME will create a bio-specimen & data repository by integrating efforts of researchers focused on the study of causes, detection, treatment, & prevention …
This is an observational study to evaluate the concordance rate between the results of performing intraoral exams by viewing live and/or recorded video footage of subjects' oral cavities and the results of standard in-person intraoral exams. Adult subjects capable of providing Informed Consent will undergo a routine intraoral exam by …
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