Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates an investigational medication for people with advanced or metastatic malignant mesothelioma or other solid tumors. The purpose of this study is to evaluate the safety, tolerability, and early effectiveness of the investigational medication. The study is conducted in two parts: a dose escalation part to determine the …
This study investigates the safety and efficacy of an investigational medication, surovatamig, administered alone or with other anticancer agents in individuals with mature B-cell malignancies. This study is open-label, meaning both researchers and participants know what treatment is being administered. It includes three substudies, each focusing on different types of …
Collect safety and efficacy data of MMAE in patients ages 40-90 years with a moderately symptomatic convexity chronic subdural hematoma (CSDH). Subjects will be randomized 1:1 to conventional surgery or MMAE treatment and followed for 180 days (+/- 30 days).
This study investigates the use of an investigational medication in patients with advanced solid tumors, specifically focusing on its effects as a single agent or in combination with other therapies. The purpose is to determine the recommended Phase II dose and to evaluate its safety, tolerability, and anti-tumor activity. The …
A randomized clinical trial designed to determine the effectiveness of real-time CGM at reducing maternal and neonatal morbidity, define an outcome-based definition for glycemic control and identify social and structural barriers to improving outcomes in a population of pregnant participants with Type 2 Diabetes
The Alzheimer's Network for Treatment and Diagnostics (ALZ-NET) will collect data from individuals evaluated for or receiving treatment with novel (or new) FDA-approved therapies for Alzheimer's disease (AD). It will follow and record information about people's health, safety, brain scans, and long-term health outcomes during their regular memory care.
This study investigates the effectiveness of two different treatment regimens for patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with conditions such as acute leukemia, chronic myelogenous leukemia, myelodysplasia, and various types of lymphoma. The purpose is to compare the use of Tacrolimus, Methotrexate, and …
This study investigates the safety and effectiveness of an investigational medication in patients with advanced blood cancers, including Non-Hodgkin Lymphoma, Multiple Myeloma, Acute Myeloid Leukemia, and high-risk Myelodysplastic Syndrome.Participants in the study will receive the investigational medication either alone or in combination with other treatments. The study will monitor the …
The objectives are to measure mitochondrial respiration and metabolomics of human pregnant myometrium at term gestation. The primary objective of this study is to measure parameters of mitochondrial respiratory capacity in live pregnant human myometrium in obese versus non-obese subjects at the time of delivery. The secondary objectives are to …
This study investigates the efficacy and safety of an investigational medication in combination with chemotherapy for treating individuals with metastatic HER2-positive breast cancer. Participants in this study have previously been treated with a specific medication called T-DXd but have either not responded or cannot tolerate it.Participants will be randomly assigned …
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