Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effectiveness of an investigational medication combined with ipilimumab in patients with metastatic pancreatic cancer. The purpose is to understand if this combination can slow tumor growth and what side effects may occur. Participants will be placed into two study arms: Arm A will receive the investigational …
This study investigates the safety and effectiveness of an investigational oral medication designed to degrade SMARCA2 in patients with advanced or metastatic solid tumors that have a SMARCA4 mutation. The purpose of this study is to understand how the investigational medication affects the body, how it is processed by the …
This study investigates the use of CART123 cells in combination with ruxolitinib for patients with relapsed or refractory acute myeloid leukemia (AML). The purpose of this study is to assess the safety and early effectiveness of this combination treatment. Participants will receive a single infusion of CART123 cells after being …
The goal of this clinical trial is to learn the effects of ketone supplement compared to placebo on alcohol withdrawal symptoms during a 4 day alcohol withdrawal management treatment in adults with moderate to severe alcohol use disorder at the Hospital of the University of Pennsylvania, Cedar Detox Center.
The objective of this study is to show that inhaled nitric oxide can increase blood flow in the brain after traumatic brain injury, attenuating brain injury and resulting in improved long-term function. We will use optical brain monitoring to determine changes in cerebral perfusion and metabolism by iNO treatment in …
This study investigates the effectiveness and safety of using Tumor Treating Fields (TTFields) in combination with pembrolizumab and platinum-based chemotherapy for treating metastatic non-small cell lung cancer (NSCLC). The purpose of this study is to assess how well patients survive overall and how long they live without the disease getting …
This study aims to assess the safety and tolerability of long-term therapy with XEN1101 in subjects with FOS or PGTCS who have completed Study XPF-010-301, XPF-010-302, or XPF-010-303. Participants MUST HAVE completed one of the prior studies in order to participate.
The study is being conducted to develop and test a telehealth tool intended to support community mental health clinicians to deliver cognitive behavioral therapy (CBT). We are interested in collaborating with clinicians and clients to test it out and get feedback on how to improve it. This tool is based …
This study investigates different dosing strategies for CDK4/6 inhibitors in older patients with metastatic breast cancer (MBC). The purpose of the study is to compare standard dosing with a titrated dosing approach to see which helps patients tolerate the medication better and continue treatment longer.Participants will be randomly assigned to …
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
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