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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Efgartigimod in GBS

99 years and younger
All genders
See Section 3: Study Objectives and Endpoints of the attached protocol. See Section 3: Study Objectives and Endpoints of the attached protocol. See Section 3: Study Objectives and Endpoints of the attached protocol.
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UPCC 25823 Advanced Renal Cell Cancer Combination ImmunoThErapy Clinical Trial (ARCITECT)

99 years and younger
All genders
This study is a randomized, open label, multicenter Phase II trial to evaluate the efficacy and safety of botensilimab (a novel Fc enhanced Tree depleting anti-CTLA4) and balstilimab (a novel anti-PD1) relative to ipilimumab and nivolumab in treatment naïve patients with metastatic ccRCC. We would like to rely on WCG …
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MVT-601A-006 MOXIE

99 years and younger
All genders
The primary objective of this study is to characterize changes in bone mineral density (BMD) during continuous treatment with relugolix combination tablet (relugolix 40 mg/estradiol [E2] 1 mg/norethindrone acetate [NETA] 0.5 mg) for up to 48 months (4 years) in two cohorts: (1) premenopausal women with heavy menstrual bleeding associated …
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UPCC 17423: An open-label phase II study to investigate the efficacy, safety, and pharmacokinetics of tirabrutinib in patients with Primary Central Nervous System Lymphoma (PCNSL)

99 years and younger
All genders
This study will evaluate the efficacy, safety, and pharmacokinetics of tirabrutinib monotherapy in patients with relapsed or refractory PCNSL (Part A), and tirabrutinib in combination with one of two different high dose methotrexate based regimens (methotrexate/ temozolomide/rituximab or rituximab/methotrexate/procarbazine/ vincristine) as first line therapy in patients with newly diagnosed, treatment …
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ENGAGE

99 years and younger
All genders
This is a phase 2/3, multicenter, randomized, 3-part study investigating the efficacy, safety, tolerability, PK, and immunogenicity of dupilumab in adults and adolescents (12 years of age) with active EoG (with or without EoD).Eosinophilic gastritis (EoG) is a rare, chronic, allergic/immune mediated disease of the stomach, distinct from eosinophilic esophagitis …
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SunRISe-4

99 years and younger
All genders
The study is being conducted to research if an investigational drug delivery system (gemcitabine/TAR-200) in combination with intravenous cetrelimab and intravenous cetrelimab alone can improve the results of radical cystectomy for participants with muscle invasive bladder cancer.
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11C-M503 PET

99 years and younger
All genders
Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C M503 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C M503 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
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An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib (UPROAR)

18 years and older
Female
Phase 2
This study aims to learn more about the use of Mirvetuximab soravtansine and Olaparib as a maintenance therapy after completion of prior therapy for recurrent platinum sensitive ovarian, peritoneal and fallopian tube cancer. Mirvetuximab soravtansine is an effective antibody drug conjugate that targets folate receptor alpha. Olaparib is one of …
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UPCC 25523: ADI-PEG 20 or Placebo Plus Gemcitabine and Docetaxel in Previously Treated Subjects with Leiomyosarcoma (ARGSARC): A Randomized, Double-Blind, Multi-Center Phase 3 Trial

99 years and younger
All genders
This is a global, multicenter, randomized, double-blind, placebo-controlled, parallel-group phase 3 trial that will compare the efficacy and safety in subjects with advanced or metastatic LMS previously treated with an anthracycline. We would like to rely on WCG as the IRB of record for this study.
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UPCC 50423: A Randomized, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Idecabtagene Vicleucel with Lenalidomide Maintenance Versus Lenalidomide Maintenance Therapy Alone in Adult Participants with Newly Diagnosed Multiple Myeloma Who

99 years and younger
All genders
The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT). We would like to …
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