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Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effects of an investigational medication, ORIC-114, on patients with advanced solid tumors that show changes in certain genes known as EGFR or HER2. The purpose of this study is to determine the best dose for Phase 2 trials and to evaluate the safety and effectiveness of …
This study investigates the use of ultrahypofractionated whole pelvis proton therapy with a brachytherapy boost for patients with high risk or unfavorable intermediate risk prostate cancer. This study aims to understand the effectiveness of this treatment method for those with a higher risk of cancer spreading to lymph nodes.Participants in …
This study investigates the safety and clinical activity of an investigational medication in participants with advanced solid tumors that have a specific genetic mutation known as KRAS G12C. The purpose of this study is to evaluate how the investigational medication works in different phases, including dose escalation and expansion, to …
This will be a prospective, observational, multicenter study. All implants will be placed in the maxilla or mandible for already established participants at Penn Dental Medicine. The patient will either have a temporary prosthesis placed (out of occlusion) immediately (during the same implant placement visit or within 48 hours) or …
This study investigates methods for screening liver cancer in patients with cirrhosis or chronic hepatitis B. The purpose of this study is to compare two screening methods: one using ultrasound and a protein marker called AFP, and another using a biomarker called GALAD. Participants will be divided into two study …
Managed Access Program (MAP) to provide access to CTL019, for acute lymphoblastic leukemia (ALL) or diffuse large b-cell lymphoma (DLBCL) patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for commercial release. The primary purpose of a MAP is to provide access to product. NA - …
This study investigates the use of an investigational medication in treating patients with Kaposi sarcoma. The purpose of this study is to evaluate how well the investigational medication works by blocking certain enzymes needed for tumor cell growth, which may stop the tumor from growing.Participants will receive the investigational medication …
This study investigates the effects of a combination of investigational medications in patients newly diagnosed with secondary acute myeloid leukemia (AML) after previous exposure to hypomethylating agents. The purpose of this study is to understand how these investigational medications work together to treat AML.Participants in the study will receive a …
This study investigates the long-term safety of investigational cell therapies in patients who have previously participated in Caribou-sponsored clinical studies, special access programs, or investigator-initiated trials (IITs). The purpose of this study is to observe patients over a period of up to 15 years after they have received their initial …
This study investigates the effects of an investigational medication on patients with relapsed and refractory multiple myeloma (RRMM). The purpose of the study is to evaluate the safety and effects of a selective inhibitor that targets a specific enzyme involved in the disease process.Participants will undergo a dose-escalation phase to …
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