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Found 930 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

LATMI-2

99 years and younger
All genders
See below. To characterize the patterns of longitudinal change in brain volume, white matter myelin content, and measures of NVU function (cerebral blood flow (CBF), CVR, BBB permeability, and extracellular free water) over the first 3 years following TBI. To determine the prognostic value of NVU measures (CBF, CVR, BBB …
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Cartesian MG-001

99 years and younger
All genders
Please refer to section 3 of the study protocol. Penn will only enroll participants into Part 3 of the study. PRIMARY OBJECTIVES The primary objective of Part 1 is to assess the safety, tolerability, and manufacturing feasibility of Descartes-08 in patients with GMG. Part 1 of the study follows an …
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UPCC 19222: A Phase 2, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination With Bevacizumab and FOLFIRI Versus Bevacizumab and FOLFIRI in Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC

99 years and younger
All genders
To evaluate the safety, tolerability, and recommended Phase 2 dose (RP2D) of magrolimab in combination with bevacizumab and FOLFIRI (5-fluorouracil [5-FU], irinotecan, and leucovorin [LV]) in previously treated patients with advanced inoperable metastatic colorectal cancer (mCRC). We would like to rely on Advarra as the IRB of record for this …
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CONDUIT vs. PEEK Cages

99 years and younger
All genders
Primary Objective: To determine if CONDUIT and PEEK +rhBMP-2 cages produce similar clinical and radiographic outcomes in patients undergoing direct lateral Interbody fusion Secondary Objective: To determine if CONDUIT and PEEK + rhBMP-2 cages are comparable with regards to cost The primary study endpoint will be the difference in fusion …
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UPCC 30423: A Phase 1/2a, Open-Label, Dose Escalation Trial of GEN3017 With Expansion Cohorts in Relapsed or Refractory CD30+ Classical Hodgkin Lymphoma and CD30+ Non- Hodgkin Lymphoma

99 years and younger
All genders
Please refer to Protocol Section 3 (Objectives and Endpoints). Please refer to Protocol Section 3 (Objectives and Endpoints). Please refer to Protocol Section 3 (Objectives and Endpoints).
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ELLIPSS

99 years and younger
All genders
The purpose of this study is to better understand molecular pathways and joint destruction in patients with autoimmune diseases such as Psoriatic Arthritis (PsA).
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Rehab CARES: In USA: Clinical Trial

99 years and younger
All genders
The Aim of this study is to validate community-based use of the haptic robot gym. We will test the safety of the haptic robot gym in a community-based rehabilitation setting. Milestones are 1) to quantify the safety of the system in terms of adverse events frequency and characteristics, 2) to …
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CBT-I AND LIGHT THERAPY

99 years and younger
All genders
A single site, 3-arm (CBT-I group; Bright Light Therapy group; Standard of Care group), parallel, randomized controlled trial in subjects with insomnia, fatigue and PAH will be conducted. Primary Objective To assess the feasibility (recruitment and retention rates) of CBT-I and Bright Light Therapy in patients with PAH. Secondary Objectives …
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S2114 A randomized Phase II Trial of Consolidation Therapy Following CD19 CAR T-Cell Treatment for Relapsed/Refractory Large B-Cell Lymphoma or Grade IIIB Follicular Lymphoma

99 years and younger
All genders
To compare the progression-free survival in participants with relapsed/refractory large B-cell lymphoma or follicular lymphoma grade 3B with stable disease (SD) or partial remission (PR) on first imaging response by central review (day +30PET/CT scan) after commercial CD19 CAR T-cell therapy
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ORARAD II

99 years and younger
All genders
This is a prospective cohort study to document long-term dental and other oral outcomes in patients who receive external beam and modern radiation therapy (RT) modalities with curative intent, as part of clinical care for a head and neck cancer. ORARAD II study will examine participants of the original cohort …
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