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Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to learn how participant factors (such as medical history and manufacturing starting material, also known as Apheresis) can predict successful manufacturing of ciltacabtagene autoleucel (Cilta-cel). This information can be used to potentially improve manufacturing processes and treat more patients with Cilta-cel. We would like …
The objectives of the study are to quantify uptake and release by the brain of approximately 277 metabolites by quantitative mass spectrometry. Change in metabolite concentration between arterial and venous samples.
This study’s goal is to identify and validate a package of implementation strategies to promote reach, effectiveness, adoption, implementation and maintenance of ASIST among Suicide Intervention Officers (SIO) in the Connecticut Army National Guard. Aim 1: Finalize our formative research to develop the implementation package for SIOs and chaplains. Hypothesis …
This study investigates the use of an investigational medication, epcoritamab, before and after CAR-T cell therapy in patients with relapsed or refractory large B-cell lymphomas. This study aims to understand if epcoritamab can improve outcomes when used in conjunction with CAR-T cell therapy, a treatment where a patient's T cells …
This study investigates the use of an investigational therapy for patients who have been diagnosed with a condition approved for treatment with this therapy, but whose therapy does not meet commercial release criteria. The purpose is to provide access to this investigational treatment under specific conditions.Participants in this study will …
To determine the response of SkM OxPhos to supplemental oxygen in HFpEF noting that an increase in SkM OxPhos with supplemental oxygen suggests the presence of mitochondrial functional reserve. Change in SkM OxPhos on CrCEST in response to supplemental oxygen Change in intramuscular perfusion with supplemental oxygen as compared to …
This study investigates a radiomics-based computer-aided diagnosis (CAD) tool used to help clinicians manage pulmonary nodules (PNs). The study compares the usual care with the use of this CAD tool to see if it improves the accuracy of assessing cancer risk in PNs.Participants in the study will be randomly assigned …
This study investigates an investigational medication for people with advanced cancers that are positive for the PRAME protein. The study aims to understand the safety and effectiveness of this investigational medication in adults who have a specific genetic marker called HLA-A*02:01 and PRAME-positive tumors.Participants in this study will receive the …
This study investigates an investigational therapy using autologous CAR T-cells targeting Cadherin 17 (CDH17) for patients with advanced gastrointestinal cancers. These cancers have either returned after treatment or did not respond to standard treatments. The study aims to evaluate the safety and effectiveness of this therapy in patients with specific …
The overarching goal of our Clinical Validation Center for Hepatocellular Carcinoma (CVC-HCC) is to develop a robust infrastructure that will support efficient validation of emerging HCC biomarkers. Our CVC-HCC will also conduct studies to validate novel blood and imaging biomarkers to improve risk stratification and early detection in patients with …
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