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Found 938 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to investigate the effectiveness and safety of an investigational medication compared to standard endocrine therapy for patients with ER+/HER2- early breast cancer. The study focuses on patients who have completed locoregional treatment, which may include surgery and radiotherapy, and are at intermediate-high or high …
Primary Objective: To determine changes in neurodegeneration over the first year of treatment with anti-amyloid monoclonal antibodies Secondary Objectives: To identify measures that detect and monitor neuroinflammation during anti-amyloid treatment. To explore the interaction between neuroinflammation and neurodegeneration Primary Endpoint: Neuroimaging and blood-based measures of neurodegeneration, cognitive performance Secondary Endpoints: …
Study on Investigational Medication for Relapsed or Refractory Plasma Cell Cancer (Multiple Myeloma)
This study investigates the effects of an investigational medication on individuals with relapsed or refractory multiple myeloma. The purpose of the study is to evaluate the safety, tolerability, and effectiveness of the investigational medication when used alone or in combination with other cancer treatments.Participants in the study will receive the …
This study investigates the safety, tolerability, and anti-tumor activity of an investigational medication in adult patients with solid tumors that express MAGE-A4, a specific tumor-associated antigen. The study focuses on individuals with the HLA-A*02:01 tissue marker, which is necessary for participation.Participants will undergo various study procedures to evaluate the maximum …
Objective:To conduct electrophysiological experiments in human patients undergoing awake brain surgery with the aim of elucidating how the various brain regions coordinate their activity during naturalistic movements.Evaluate the effectiveness of various electrode arrays for recording of cortical activity.How the brain coordinates body movements and processes sensations such as touch.How the …
This study investigates the use of a medical device containing yttrium-90 for treating liver cancer, specifically Hepatocellular Carcinoma (HCC). The purpose of this study is to evaluate the safety and effectiveness of Eye90 microspheres, which deliver localized radiation therapy directly to liver tumors. This approach is used for patients whose …
This is an OLE for all subjects we currently have enrolled in BI 1305-0014 and 1305-0023. Subjects will be on either 9 mg or 18 mg of IP based on results from the current studies. Procedures involve safety labs, lung function testing, clinical labs, ECGs, PEs, AE collection.
The primary objective of the IMPROVE-AD trial is to determine whether an upfront invasive strategy of TEVAR plus medical therapy reduces the occurrence of a composite endpoint of all-cause death or major aortic complications compared to an upfront conservative strategy of medical therapy with surveillance for deterioration in patients with …
This study investigates the effectiveness of adding an investigational medication to the standard treatment for patients with metastatic pancreatic cancer who have specific genetic mutations known as BRCA1 or BRCA2. The purpose of this study is to see if the combination of an investigational medication with olaparib, a targeted therapy …
This study investigates providing access to axicabtagene ciloleucel, an investigational medication, for patients who have a disease approved for treatment with this medication but whose product does not meet commercial release criteria. The purpose is to allow patients to receive treatment with axicabtagene ciloleucel that is otherwise unavailable due to …
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