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Found 938 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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A Randomized, Open-Label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy
18 years - 100 years
Female
Phase 3
The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer …
18 years or above
All genders
Phase 2/3
Interventional
This study investigates treatments for non-small cell lung cancer (NSCLC) by using a method called genomic screening. The purpose of this study is to determine which type of cancer trait, known as a biomarker, a participant has. This information helps assign participants to different sub-studies within a larger protocol called …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness, safety, and how the body processes an investigational medication in patients with Primary Central Nervous System Lymphoma (PCNSL). The study has two parts: Part A involves patients with PCNSL that has returned or not responded to previous treatments, and Part B involves patients who have …
99 years or below
All genders
The overall study objectives include evaluating the long-term safety and tolerability of Staccato alprazolam in patients with stereotypical prolonged epilepsy. The study will evaluate the probability of success of repeated treatment with Staccato alprazolam and of repeated treatment with Staccato alprazolam with no recurrence of seizure(s) up to 2 hours …
18 years or above
Female
Phase 2
This study aims to learn more about the use of Mirvetuximab soravtansine and Olaparib as a maintenance therapy after completion of prior therapy for recurrent platinum sensitive ovarian, peritoneal and fallopian tube cancer. Mirvetuximab soravtansine is an effective antibody drug conjugate that targets folate receptor alpha. Olaparib is one of …
50 years - 75 years
All genders
Observational
This study investigates different methods for monitoring pancreatic cysts. Monitoring these cysts is important to prevent complications. The purpose of this study is to compare two approaches: more frequent monitoring versus less frequent monitoring, to see which one leads to better outcomes for patients with pancreatic cysts.Participants in the study …
UPCC 28922 AbatacepT foR ImmUne checkpoint inhibitor associated Myocarditis (ATRIUM): A Phase 3, Investigator-Initiated, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Abatacept Compared to Placebo in Participants with Immune Checkpoint Inhibitor Associated Myocarditis
18 years or above
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication compared to a placebo in participants with myocarditis linked to immune checkpoint inhibitors (ICI). This condition can occur as a side effect of cancer treatments that use ICIs to enhance the body's immune response against cancer cells. The purpose of this …
18 years or above
All genders
Phase 2
Interventional
This study investigates an investigational medication for patients with HER2-positive metastatic breast cancer. The purpose of this study is to evaluate the effects of this investigational medication in patients who have previously been treated with a specific therapy called T-DXd.Participants in this study will receive the investigational medication through an …
99 years or below
All genders
The purpose of this study is understand changes in cognition, physical abilities, and quality of life of individuals receiving venetoclax-based chemotherapy.
18 years - 60 years
Female
Phase 3
Interventional
This study investigates the effectiveness of adding adjuvant chemotherapy to ovarian function suppression and endocrine therapy in premenopausal patients with early-stage, estrogen receptor-positive, HER2-negative breast cancer. The study focuses on patients with specific Oncotype recurrence scores, which help predict the risk of cancer returning.Participants in the study will receive ovarian …
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